Results 61 to 70 of about 943,536 (329)

Development of Efficient Genome-Reduction Tool Based on Cre/loxP System in Rhodococcus erythropolis [PDF]

, 2023
Wataru Kitagawa, Miyako Hata
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Constraints on dark matter models from a Fermi LAT search for high-energy cosmic-ray electrons from the Sun

, 2011
During its first year of data taking, the Large Area Telescope (LAT) onboard the Fermi Gamma-Ray Space Telescope has collected a large sample of high-energy cosmic-ray electrons and positrons (CREs).
A. Bouvier, A. Chekhtman, A. de Angelis, A. M. Lionetto, A. Morselli, A. P. Waite, A. Reimer, A. S. Johnson, A. W. Borgland, B. Berenji, B. L. Winer, C. Cecchi, C. D. Dermer, C. Favuzzi, C. Monte, C. Sgrò, D. Bastieri, D. Hadasch, D. J. Suson, D. Paneque, E. Bonamente, E. Bottacini, E. Charles, E. D. Bloom, E. do Couto e Silva, E. J. Siskind, E. Nuss, E. Orlando, E. Troja, F. de Palma, F. Gargano, F. Giordano, F. Longo, F. Loparco, F. Piron, G. A. Caliandro, G. Barbiellini, G. Cowan, G. Godfrey, G. Iafrate, G. Jóhannesson, G. Spandre, G. Tosti, G. Vianello, G. B. Rybicki, H. Katagiri, H. Takahashi, I. A. Grenier, I. V. Moskalenko, J. B. Thayer, J. Bregeon, J. Cohen-Tanugi, J. E. McEnery, J. F. Ormes, J. G. Thayer, J. H. Panetta, J. Kataoka, J. P. Norris, J. Siegal-Gaskins, J. Vandenbroucke, K. S. Wood, L. Baldini, L. Latronico, L. Tibaldo, M. Ajello, M. Brigida, M. E. Monzani, M. Giroletti, M. Gustafsson, M. Kuss, M. N. Lovellette, M. N. Mazziotta, M. Naumann-Godo, M. Ozaki, M. Pesce-Rollins, M. Pierbattista, M. Razzano, N. Gehrels, N. Giglietto, N. Omodei, N. Vilchez, O. Reimer, P. A. Caraveo, P. Bruel, P. D. Smith, P. Duffett-Smith, P. F. Michelson, P. Fusco, P. Lubrano, P. S. Drell, P. Spinelli, P. Wang, R. A. Cameron, R. Bellazzini, R. Bernabei, R. Buehler, R. Claus, R. D. Blandford, R. Rando, S. Buson, S. Ciprini, S. Cutini, S. Germani, S. Guiriec, S. J. Fegan, S. Murgia, S. Rainò, S. Ritz, S. W. Digel, S. Zimmer, T. Glanzman, T. Kamae, T. L. Schalk, T. L. Usher, T. Mizuno, T. Ohsugi, T. Tanaka, V. Vasileiou, W. B. Atwood, W. B. Focke, Y. Fukazawa, Z. Yang   +121 more
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Evaluating The Role of Fosfomycin in Treating MDR Urinary Pathogens: A Tertiary Care Hospital Perspective

Journal of Pure and Applied Microbiology
Urinary tract infections (UTIs) are most common infections encountered in both community and hospital settings and are frequently treated with antibiotics.
Susmitha Simgamsetty, Sai Vineela Pilli, Muthusamy Raman, Padmaja Yarlagadda   +3 more
doaj   +1 more source

Embracing Mapalus tradition management values for Christian religious education

HTS Teologiese Studies/Theological Studies, 2022
The relationship between religion and education in the Minahasa community still receives inadequate attention. One local wisdom that has experienced degradation of its noble values over the years is the mapalus culture.
Christar A. Rumbay, Harol Lumapow, Philoteus E.A. Tuerah, Elni J. Usoh, Viktory N.J. Rotty, Jeffry S.J. Lengkong   +5 more
doaj   +1 more source

Endothelium‐specific Cre recombinase activity in flk‐1‐Cre transgenic mice [PDF]

Developmental Dynamics, 2004
AbstractThe use of the Cre‐loxP recombination system allows the conditional inactivation of genes in mice. The availability of transgenic mice in which the Cre recombinase expression is highly cell type specific is a prerequisite to successfully use this system.
Alexander H, Licht, Sabine, Raab, Ursula, Hofmann, Georg, Breier   +3 more
openaire   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Assessing Risk Factors and Clinical Implications of Carbapenem-resistant Enterobacterales Infections in a Tertiary Care Setting

Journal of Pure and Applied Microbiology
Carbapenem-resistance in Gram-negative bacteria poses a global threat, necessitating vigilant surveillance for informed policy decisions. Our study investigated clinically significant, carbapenem-resistant Enterobacterales infections.
Sevitha Bhat, Joanne Mathew, Nigitha Prasad, K. Archana Bhat, Shalini Shenoy Mulki   +4 more
doaj   +1 more source