Results 81 to 90 of about 997,878 (328)
Phosphorylation of CREB affects its binding to high and low affinity sites [PDF]
, 1992 Cyclic AMP treatment of hepatoma cells leads to increased protein binding at the cyclic AMP response element (CRE) of the tyrosine aminotransferase (TAT) gene in vivo, as revealed by genomic footprinting, whereas no increase is observed at the CRE of the
Boshart, Michael +7 more
core
Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism [PDF]
, 2013 Arginase deficiency is a rare autosomal recessive disorder resulting from a loss of the liver arginase isoform, arginase 1 (ARG1), which is the final step in the urea cycle for detoxifying ammonia. ARG1 deficiency leads to hyperargininemia, characterized
Ballantyne, Laurel L. +6 more
core +2 more sources
Advanced Functional Materials, EarlyView.This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Journal of Pure and Applied MicrobiologyCarbapenem-resistance in Gram-negative bacteria poses a global threat, necessitating vigilant surveillance for informed policy decisions. Our study investigated clinically significant, carbapenem-resistant Enterobacterales infections.
Sevitha Bhat +4 more
doaj +1 more source
Indian Journal of Health Sciences and Biomedical Research KLEU, 2020 INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample.
Girish Konasagara Shanthaveeranna +1 more
doaj +1 more source
The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. [PDF]
, 2016 The mitochondrial translocator protein (TSPO) has been implicated in CNS diseases. Here, we sought to determine the specific role of TSPO in experimental autoimmune encephalomyelitis (EAE), the most studied animal model of multiple sclerosis (MS).
Chechneva, Olga +3 more
core +1 more source
Advanced Functional Materials, EarlyView.The shape of guanine self‐assemblies is tuned by introducing alkyl (G8), fluoroalkyl (G8f), and oligoether (G8g) side chains into the G moiety. The scanning tunneling microscopy results and calculations show that the presence and type of the side chain strongly affect the G self‐assembly network.
So‐Huei Kang +9 more
wiley +1 more source
EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA): a protocol of a European multicentre observational study [PDF]
, 2017 Introduction: The rapid worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) constitutes a major challenge. The aim of the EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA), which is part
Bravo Ferrer, José +4 more
core
, 2014 We measured the He and Ne concentrations of 50 individual extraterrestrial chromite grains recovered from mid-Ordovician (lower Darriwilian) sediments from the Lynna River section near St. Petersburg, Russia. High concentrations of solar wind-like He and
Lindskog, Anders +4 more
core +1 more source
A GABAergic projection from the centromedial nuclei of the amygdala to ventromedial prefrontal cortex modulates reward behavior [PDF]
, 2016 The neural circuitry underlying mammalian reward behaviors involves several distinct nuclei throughout the brain. It is widely accepted that the midbrain dopamine (DA) neurons are critical for the reward-related behaviors.
Bhatti, Dionnet L +9 more
core +2 more sources