Results 21 to 30 of about 3,359,359 (198)

Studying protein-protein interactions using peptide arrays [PDF]

, 2010
Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T., Rudiger, S.G.D., Sub Cellular Protein Chemistry, Rotem-Bamberger, S., Katz, C., Friedler, A., Levy-Beladev, L., Cellular Protein Chemistry   +7 more
core   +1 more source

Comparison of short‐course antibiotic therapy of 6 or less days with a longer treatment in patients with cholangitis after liver transplantation

Transplant Infectious Disease, Volume 24, Issue 4, August 2022., 2022
Abstract Objectives Stenosis of the biliary anastomosis predisposes liver graft recipients to bacterial cholangitis. Antibiotic therapy (AT) is performed according to individual clinical judgment, but duration of AT remains unclear. Methods All liver graft recipients with acute cholangitis according to the Tokyo criteria grade 1 and 2 after endoscopic ...
Philip G. Ferstl, Alexander Queck, Katharina Bremer, Natalie Filmann, Nina Weiler, Martin‐W. Welker, Oliver Waidmann, Mate Knabe, Wolf O. Bechstein, Michael Hogardt, Volkhard A. J. Kempf, Stefan Zeuzem, Jonel Trebicka, Mireen Friedrich‐Rust, Dirk Walter   +14 more
wiley   +1 more source

C-reactive protein is essential for innate resistance to pneumococcal infection. [PDF]

, 2014
No deficiency of human C-reactive protein (CRP), or even structural polymorphism of the protein, has yet been reported so its physiological role is not known.
Lawrence, Rachel A., Read, Kevin D., Aviva Petrie, Pepys, M B, Pepys, MB, Hutchinson, Winston L., LSHTM, Read, Kevin D, Raynes, JG, Read, KD, J. Brian Souza, Tennent, G A, Stephan Ellmerich, Loeffler, JM, Simons, JP, Rachel A. Lawrence, Simons, J Paul, Tennent, GA, John G. Raynes, Dundee, Glenys A. Tennent, Ellmerich, Stephan, Ellmerich, S, Tennent, Glenys A, Al-Shawi, Raya, Petrie, A, Tennent, Glenys A., Simons, J. Paul, Lawrence, R A, Jutta M. Loeffler, Lawrence, RA, Hutchinson, Winston L, J. Paul Simons, de Souza, J Brian, de Souza, J. Brian, Kevin D. Read, Raynes, John G., Raynes, J G, Read, K D, Mark B. Pepys, Hutchinson, WL, de Souza, JB, Loeffler, Jutta M, Petrie, Aviva, Al-Shawi, R, Pepys, Mark B., Lawrence, Rachel A, Raynes, John G, Loeffler, J M, de Souza, J B, Hutchinson, W L, Pepys, Mark B, Raya Al‐Shawi, Winston L. Hutchinson, Loeffler, Jutta M., Simons, J P, UCL   +56 more
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A case of methotrexate‐associated Epstein‐Barr virus‐positive mucocutaneous ulcer

Skin Health and Disease, Volume 2, Issue 2, June 2022., 2022
Abstract Epstein‐Barr virus‐positive mucocutaneous ulcer (EBVMCU) is a B‐cell proliferative disorder that has been designated as a provisional entity in the 2017 World Health Organization classification for lymphoid neoplasms. While EBVMCU may contain varying numbers of cells with Hodgkin and Reed‐Sternberg cells‐like morphology, the clinical course is
Keiko Sakamoto, Takeshi Baba, Hiroaki Takatori, Keisuke Nagao, Junko Misawa, Tetsuya Honda   +5 more
wiley   +1 more source

CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]

, 2018
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry, Hendershot, Linda M., Feige, Matthias J., Ineke Braakman, Matthias J. Feige, Braakman, Ineke, Cellular Protein Chemistry, Linda M. Hendershot   +7 more
core   +1 more source

Therapeutic Lowering of C-Reactive Protein

Frontiers in Immunology, 2021
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectious ...
Rachel V. Jimenez, Alexander J. Szalai
doaj   +1 more source

Acute phase protein response and changes in lipoprotein particle size in dogs with systemic inflammatory response syndrome

Journal of Veterinary Internal Medicine, Volume 36, Issue 3, Page 993-1004, May/June 2022., 2022
Abstract Background Improved methodology to measure acute phase proteins and determination of lipoprotein particle‐size distribution (PSD) could be clinically useful in dogs with systemic inflammatory processes. Objectives Evaluate an immunoturbidometric assay for serum amyloid A (SAA) and lipoprotein PSD in dogs with sepsis, nonseptic systemic ...
Erica Behling‐Kelly, Carol E. Haak, Patrick Carney, Jessica Waffle, Kelly Eaton, Robert Goggs   +5 more
wiley   +1 more source

Genetic variation in Fcγ receptor IIa and risk of coronary heart disease : negative results from two large independent populations [PDF]

, 2009
Background The role of the Fcgamma receptor IIa (FcgammaRIIa), a receptor for C-reactive protein (CRP), the classical acute phase protein, in atherosclerosis is not yet clear.
Hoffmann, Michael Marcus, Karakas, M., Hoffmann, M.M., Khuseyinova, N., Illig, Thomas, Bernhard Winkelmann, Karakas, Mahir, Thomas Illig, Vollmert, C., Christa Meisinger, Koenig, W., Mahir Karakas, März, Winfried, Caren Vollmert, Winkelmann, Bernhard, Meisinger, C., Winkelmann, B., Hoffmann, Michael M., Khuseyinova, Natalie, Natalie Khuseyinova, Rothenbacher, D., Illig, T., Bernhard O Böhm, Böhm, Bernhard O., Vollmert, Caren, Koenig, Wolfgang, Böhm, Bernhard Otto, Rothenbacher, Dietrich, Marz, W., Michael M Hoffmann, Meisinger, Christine, König, Wolfgang, Meisinger, Christa, Böhm, B.O., Dietrich Rothenbacher, Wolfgang Koenig, Winkelmann, Bernhard Rudolf, Winfried März, Winkelmann, Bernhard R.   +38 more
core   +2 more sources

Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? [PDF]

, 2009
<p><b>Background:</b> Circulating inflammatory markers may more strongly relate to risk of fatal versus nonfatal cardiovascular disease (CVD) events, but robust prospective evidence is lacking.
Jukema, J.W., Westendorp, R.G.J., Lowe, G.D., Murray, H.M., Cobbe, S., de Craen, A.J.M., Blauw, G.J., Ford, I., Welsh, P.I., Murphy, M.B., Buckley, B.M., Macfarlane, P.W., Stott, D.J., Sattar, N.A., Shepherd, J., Gerard J Blauw, Chris J Packard, Ian Ford, Ford Ian, David J Stott, Sattar Naveed, Welsh Paul, Stuart Cobbe, Westendorp Rudi G. J., Lowe Gordon D., Heather M Murray, Paul Welsh, Murphy Michael B., Macfarlane Peter W., Peter W Macfarlane, James Shepherd, Buckley Brendan M., Stott David J., Cobbe Stuart, Jukema J. Wouter, J Wouter Jukema, Murray Heather M., Anton J M de Craen, de Craen Anton J. M., Packard Chris J., Naveed Sattar, Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group, Blauw Gerard J., Brendan M Buckley, Michael B Murphy, Rudi G J Westendorp, Gordon D Lowe, Shepherd James   +47 more
core   +2 more sources

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias, Sub Cellular Protein Chemistry, Kityk, R., Rüdiger, S.G.D., Morán Luengo, T., Cellular Protein Chemistry   +5 more
core   +2 more sources