Expressed protein ligation for a large dimeric protein [PDF]
, 2011 Expressed protein ligation (EPL) is a protein engineering tool for post-translational ligation of protein or peptide fragments. This technique allows modification of specific parts of proteins, opening possibilities for incorporating probes for ...
NMR Spectroscopy +11 more
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Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N‑Glycosidic Bond of 8‑OxoG with the hOGG1 DNA Repair Protein [PDF]
, 2012 A mechanistic pathway for cleavage of the N-glycosidic bond of 8-oxo-2′-deoxyguanosine (oxoG) catalyzed with the human 8-oxoguanine glycosylase 1 DNA repair protein (hOGG1) is proposed in this theoretical study. The reaction scheme suggests direct proton
Sychrovský, V. +5 more
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Dependence of C-Reactive Protein & Cholesterol [PDF]
Kirkuk Journal of Science, 2011 This study had been designed to illustrate the relationship between immunological and biochemical abnormalities in patients with coronary heart disease (CHD) in Dohuk. These patients were referred to the general Azadi hospital in Dohuk for investigation.
Malika K. Najeeb Al Barwari +1 more
doaj +1 more source
Picky Hsp90-Every Game with Another Mate [PDF]
, 2017 In this issue of Molecular Cell, Sahasrabudhe et al. (2017) present a dramatically renovated functional cycle for the molecular chaperone Hsp90, which stimulates re-thinking of the mechanism of this vital protein folding ...
Sub Cellular Protein Chemistry +3 more
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Domain discovery method for topological profile searches in protein structures [PDF]
, 2004 We describe a method for automated domain discovery for topological profile searches in protein structures. The method is used in a system TOPStructure for fast prediction of CATH classification for protein structures (given as PDB files).
Viksna, J, Gilbert, D, Torrance, G
core +6 more sources
Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and in HuH7 cells. [PDF]
, 2013 Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through ...
Enrich Bastús, Carles +41 more
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OSTEOPOROSIS AND C-REACTIVE PROTEIN
Научно-практическая ревматология, 2010 A chronic inflammatory process is one of the risk factors of secondary osteoporosis (OP) and its related fractures. Determination of the level of C-reactive protein (CRP) is used to estimate the magnitude of an inflammatory reaction. The developed highly
S G Anikin +5 more
doaj +1 more source
C-Reactive protein and genetic variants and cognitive decline in old age: the PROSPER Study [PDF]
, 2011 Background: Plasma concentrations of C-reactive protein (CRP), a marker of chronic inflammation, have been associated with cognitive impairment in old age. However, it is unknown whether CRP is causally linked to cognitive decline.
van Himbergen Thomas +46 more
core +2 more sources
Qualitative C-reactive protein as a marker of neonatal sepsis in a tertiary neonatal unit in Sudan
Healthcare in Low-resource Settings, 2013 Sepsis is one of the most common causes of morbidity and mortality in newborns. Diagnosis of neonatal sepsis may be difficult because clinical presentations are often non-specific.
Abdelmoneim E. Kheir +3 more
doaj +1 more source
A Hospital-Based Assessment of Diagnostic Efficacy of Hematological Biomarkers, Coagulation Profile and CRP (CReactive Protein) in COVID-19 Patients [PDF]
, 2023 Aim: In this study, the roles of biomarkers from a peripheral blood sample were used in the diagnosis of COVID-19 patients who have history of fever and have been admitted to hospital are examined. Methods: The present study was conducted Department of Pathology, AIIMS, Patna, Bihar, India where the patients having history of fever were admitted during
openaire +1 more source