Results 91 to 100 of about 187,646 (253)
An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer +12 more
wiley +1 more source
Incision wounds are a type of open wound that requires treatment to prevent infection and accelerate healing. Using natural ingredient-based creams has become a more practical alternative to conventional ointments.
Husna Rizki, Harlita Harlita
doaj +1 more source
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
This study presents the formulation of two natural antioxidant creams based on an oil-in-water emulsion system, incorporating either hydroxycitrate (HCA) from Garcinia cambogia (Gaertn.) or red wine powder (RWP) derived from Aglianico del Vulture red ...
Ilaria Pappalardo +5 more
doaj +1 more source
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Mardin Müzesi Minyatür Cam Kapları: Tipolojik ve Teknolojik Bir İnceleme
Türkiye’nin güneydoğu coğrafyasında, Anadolu ve Mezopotamya uygarlıkları arasında stratejik bir köprü konumunda yer alan Mardin, kadim tarihi boyunca sayısız medeniyete ev sahipliği yapmış önemli bir kent merkezidir.
Kasım Eker
doaj +1 more source
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing +9 more
wiley +1 more source
Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici +4 more
wiley +1 more source
Background and Aim: Cream is a rich dairy product with the pH close to neutral and limited preservation capability. Cream is suitable and rich for microbial growth.
Mohammad Mehdi Soltan Dallal +4 more
doaj
The main goal of this study was to develop methods for quality control of naftifine hydrochloride in solution and cream forms, focusing on “Quantitative Determination” and “Related Impurities.” New, precise, accurate, and environmentally friendly high ...
Oleksandra Havrylenko +3 more
doaj +1 more source

