Results 301 to 310 of about 339,433 (382)

Taxogenomic Analysis of a Novel Yeast Species, Lachancea rosae Sp. Nov. F.A., Isolated From the Wild Rose Rosa californica

open access: yesYeast, EarlyView.
The discovery, description, and taxogenomic analysis of a novel species of Lachancea revealed correlations between gene content and carbon and nitrogen physiological assays. ABSTRACT A novel Saccharomycotina yeast strain, yHQL494, was isolated from the rose hip of the wild rose Rosa californica from Castle Crags State Park, California, USA ...
Yakendra Bajgain   +10 more
wiley   +1 more source

Data privacy model using blockchain reinforcement federated learning approach for scalable internet of medical things

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract Internet of Medical Things (IoMT) has typical advancements in the healthcare sector with rapid potential proof for decentralised communication systems that have been applied for collecting and monitoring COVID‐19 patient data. Machine Learning algorithms typically use the risk score of each patient based on risk factors, which could help ...
Chandramohan Dhasaratha   +9 more
wiley   +1 more source

The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression

open access: yesAging Cell, EarlyView.
A multi‐omics analysis was performed to uncover the molecular landscape of human cardiac ageing. We report several insights for the first time: a decrease in proteins composing the structural machinery of the heart; a likely compensatory increase in energetic flux and redox reductive capacity; and an increase in lysosomal activity.
Cassandra Malecki   +20 more
wiley   +1 more source

Muscle Cathepsin B Treatment Improves Behavioral and Neurogenic Deficits in a Mouse Model of Alzheimer's Disease

open access: yesAging Cell, EarlyView.
Targeting muscle with Cathepsin B (Ctsb) to treat the AD mouse brain. In this study, an AAV‐vector‐mediated approach, utilized to express Ctsb in muscle, prevented mnemonic and neurogenic deficits and normalized hippocampal, muscle, and plasma proteomic profiles.
Alejandro Pinto   +16 more
wiley   +1 more source

A Nuclear Hormone Receptor nhr‐76 Induces Age‐Dependent Chemotaxis Decline in C. elegans

open access: yesAging Cell, EarlyView.
A forward genetic screen in C. elegans identified a nuclear hormone receptor, nhr‐76, as a gene that programs age‐dependent behavioral decline. In post‐reproductive adults, NHR‐76 downregulates odr‐10 that encodes an odorant receptor, leading to impaired chemotaxis.
Rikuou Yokosawa, Kentaro Noma
wiley   +1 more source

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