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THE CREATINE-CREATINE PHOSPHATE ENERGY SHUTTLE [PDF]
PERSPECTIVES AND SUMMARY ...... . . . . . . . . . . . 832 CREATINE KINASE.. . . ...... . . . . . . . . . .... . . . . . . . . . . ...... 833 CREATINE AND CREATINE PHO SPHATE . . . . . . . . . . . 835 COMPARTMENTATION OF CELLUL AR ENERGY METABOLISM....... . . 836 THE CREATINE PHO SPH ATE SHUTTLE . . . . . . . . . . . . . . . . . . . . . .
Samuel P. Bessman +1 more
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Creatine and the creatine transporter: A review
Molecular and Cellular Biochemistry, 2001The cellular role of creatine (Cr) and Cr phosphate (CrP) has been studied extensively in neural, cardiac and skeletal muscle. Several studies have demonstrated that alterations in the cellular total Cr (Cr + CrP) concentration in these tissues can produce marked functional and/or structural change.
Snow, Rodney., Murphy, Robyn Maree.
openaire +3 more sources
Amino Acids, 2011
Creatine monohydrate (Cr), the most diffuse supplement in the sports industry, is receiving greater attention because of its beneficial effects in a wide number of human degenerative diseases and conditions. These effects can be barely explained on the basis of the sole ergogenic role of the Cr/CrP system.
SESTILI, PIERO +6 more
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Creatine monohydrate (Cr), the most diffuse supplement in the sports industry, is receiving greater attention because of its beneficial effects in a wide number of human degenerative diseases and conditions. These effects can be barely explained on the basis of the sole ergogenic role of the Cr/CrP system.
SESTILI, PIERO +6 more
openaire +5 more sources
Cell Metabolism, 2020
Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying molecular mechanisms have not been elucidated.
Olivia A Maguire +24 more
semanticscholar +1 more source
Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying molecular mechanisms have not been elucidated.
Olivia A Maguire +24 more
semanticscholar +1 more source
Creatine, Creatine Kinase, and Aging
2018With an ever aging population, identifying interventions that can alleviate age-related functional declines has become increasingly important. Dietary supplements have taken center stage based on various health claims and have become a multi-million dollar business.
Ritu A. Shetty +2 more
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Brain creatine phosphate and creatine kinase in mice fed an analogue of creatine
Brain Research, 1989Brain phosphocreatine (PCr) concentration and creatine kinase (CK) activity have been studied by 31P nuclear magnetic resonance (NMR) spectroscopy in mice fed an analogue of creatine, beta-guanidinopropionic acid (GPA). The phosphorylated analogue (GPAP), which almost completely replaces PCr in skeletal muscle, is a poor substrate for CK.
Holtzman, D +5 more
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Creatine metabolism and the consequences of creatine depletion in muscle
Molecular and Cellular Biochemistry, 1994Currently, considerable research activities are focussing on biochemical, physiological and pathological aspects of the creatine kinase (CK)-phosphorylcreatine (PCr)-creatine (Cr) system (for reviews see [1,2]), but only little effort is directed towards a thorough investigation of Cr metabolism as a whole.
Markus Wyss, Theo Wallimann
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2007
Research has demonstrated that creatine supplementation has some therapeutic benefit with respect to muscle function and more recently neurological function. Despite the growing body of literature on the pharmacologic effect of creatine, very little is known about the disposition of creatine after supraphysiologic doses.
Wesley McCall, Adam M. Persky
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Research has demonstrated that creatine supplementation has some therapeutic benefit with respect to muscle function and more recently neurological function. Despite the growing body of literature on the pharmacologic effect of creatine, very little is known about the disposition of creatine after supraphysiologic doses.
Wesley McCall, Adam M. Persky
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