Results 341 to 350 of about 348,599 (377)
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Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer.

Cell Metabolism, 2020
Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying molecular mechanisms have not been elucidated.
Olivia A. B. Maguire   +24 more
semanticscholar   +1 more source

Creatine and the creatine transporter: A review

Molecular and Cellular Biochemistry, 2001
The cellular role of creatine (Cr) and Cr phosphate (CrP) has been studied extensively in neural, cardiac and skeletal muscle. Several studies have demonstrated that alterations in the cellular total Cr (Cr + CrP) concentration in these tissues can produce marked functional and/or structural change.
Snow, Rodney., Murphy, Robyn Maree.
openaire   +2 more sources

Creatine, Creatine Kinase, and Aging

2018
With an ever aging population, identifying interventions that can alleviate age-related functional declines has become increasingly important. Dietary supplements have taken center stage based on various health claims and have become a multi-million dollar business.
Nathalie, Sumien   +2 more
openaire   +2 more sources

The creatine phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis

Nature Metabolism, 2019
Pancreatic ductal adenocarcinoma is particularly metastatic, with dismal survival rates and few treatment options. Stiff fibrotic stroma is a hallmark of pancreatic tumours, but how stromal mechanosensing affects metastasis is still unclear.
Vassilis Papalazarou   +7 more
semanticscholar   +1 more source

Beyond muscle: the effects of creatine supplementation on brain creatine, cognitive processing, and traumatic brain injury

European Journal of Sport Science, 2018
The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research ...
E. Dolan, B. Gualano, E. Rawson
semanticscholar   +1 more source

Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain and muscle

Medicinal research reviews (Print), 2019
Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and neuronal cells.
M. Balestrino, E. Adriano
semanticscholar   +1 more source

Creatine Kinase Revisited

Journal of Clinical Neuromuscular Disease, 2001
Creatine kinase (CK) is the single most important biochemical test in the evaluation of patients with myopathies. In health, serum CK concentration is higher in men, blacks, muscular individuals, and athletes. Idiopathic hyperCKemia is an entity restricted to asymptomatic patients with a negative family history for a neuromuscular disease acid normal ...
B, Katiriji, M M, Al Jaberi
openaire   +2 more sources

Creatine kinase isoenzymes

Journal of Chromatography B: Biomedical Sciences and Applications, 1988
Analytical methods for and the clinical significance of ATP:creatine-N-phosphotransferase (EC 2.7.3.2, CK) isoenzymes have been described. The main assay methods for the isoenzymes are electrophoresis, ion-exchange chromatography and immunoinhibition.
F, Kanemitsu, T, Okigaki
openaire   +2 more sources

Creatine Kinase Isoenzymes

Clinics in Laboratory Medicine, 1986
Creatine kinase (CK), a widely distributed enzyme in the body, has its highest activities in skeletal muscle and myocardium; when serum CK activities are abnormally increased, injury to these organs must be part of the differential diagnosis. The isoenzyme CK-MB is the most important biochemical test in the diagnosis of acute myocardial infarction.
J A, Lott, L B, Abbott
openaire   +2 more sources

Effects of Creatine Supplementation on Renal Function: A Systematic Review and Meta-Analysis.

Journal of renal nutrition, 2019
Creatine supplements are intended to improve performance, but there are indications that it can overwhelm liver and kidney functions, reduce the quality of life, and increase mortality.
Alexandre de Souza E Silva   +7 more
semanticscholar   +1 more source

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