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CRC Critical Reviews in Clinical Laboratory Sciences, 1982
Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Current Sports Medicine Reports, 2013
Creatine monohydrate is a dietary supplement that increases muscle performance in short-duration, high-intensity resistance exercises, which rely on the phosphocreatine shuttle for adenosine triphosphate. The effective dosing for creatine supplementation includes loading with 0.3 g·kg·d for 5 to 7 days, followed by maintenance dosing at 0.03 g·kg·d ...
Matthew, Hall, Thomas H, Trojian
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Creatine monohydrate is a dietary supplement that increases muscle performance in short-duration, high-intensity resistance exercises, which rely on the phosphocreatine shuttle for adenosine triphosphate. The effective dosing for creatine supplementation includes loading with 0.3 g·kg·d for 5 to 7 days, followed by maintenance dosing at 0.03 g·kg·d ...
Matthew, Hall, Thomas H, Trojian
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Medicinal research reviews (Print), 2019
Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and neuronal cells.
M. Balestrino, E. Adriano
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Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and neuronal cells.
M. Balestrino, E. Adriano
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1982
There are two viewpoints regarding the role of the enzyme creatine Phosphokinase (CPK), which catalyzes the reversible transphosphorylation of creatine and adenine nucleotides in energy transport. The classical viewpoint (Fig. 1) regards CPK as a near equilibrium enzyme buffering cytosolic changes in nucleotide concentration (1,2), with creatine ...
Paul J. Geiger +3 more
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There are two viewpoints regarding the role of the enzyme creatine Phosphokinase (CPK), which catalyzes the reversible transphosphorylation of creatine and adenine nucleotides in energy transport. The classical viewpoint (Fig. 1) regards CPK as a near equilibrium enzyme buffering cytosolic changes in nucleotide concentration (1,2), with creatine ...
Paul J. Geiger +3 more
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Creatine Phosphate−Creatine Kinase in Enzymatic Synthesis of Glycoconjugates [PDF]
Organic Letters, 2003 [reaction: see text] Enzymatic production of glycoconjugates is hampered by expensive phosphagens such as acetyl phosphate (AcP) and phosphoenolpyruvate (PEP). Here, we introduce creatine phosphate--creatine kinase system as a novel and practical energy source in carbohydrate synthesis.
Yingxin Zhang +4 more
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Creatine transporters: A reappraisal
Molecular and Cellular Biochemistry, 2004Creatine (Cr) plays a key role in cellular energy metabolism and is found at high concentrations in metabolically active cells such as skeletal muscle and neurons. These, and a variety of other cells, take up Cr from the extra cellular fluid by a high affinity Na(+)/Cl(-)-dependent creatine transporter (CrT). Mutations in the crt gene, found in several
Speer, Oliver +7 more
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Brain Creatine Kinase and Creatine Transporter Proteins in Normal and Creatine-Treated Rabbit Pups
Developmental Neuroscience, 2000Systemic creatine (Cr) supplementation increases brain phosphocreatine (PCr) and prevents hypoxic seizures in 15-day-old rabbits . Between 5 and 30 days of age during normal development, rabbit gray matter mitochondrial creatine kinase (Mi-CK) increases 400% while cytosolic CK (BB-CK) increases 60%.
David M. Holtzman +3 more
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Current protein and peptide science, 2017
Creatine, a very popular supplement among athletic populations, is of growing interest for clinical applications. Since over 90% of creatine is stored in skeletal muscle, the effect of creatine supplementation on muscle metabolism is a widely studied ...
F. Farshidfar, Mark A Pinder, S. Myrie
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Creatine, a very popular supplement among athletic populations, is of growing interest for clinical applications. Since over 90% of creatine is stored in skeletal muscle, the effect of creatine supplementation on muscle metabolism is a widely studied ...
F. Farshidfar, Mark A Pinder, S. Myrie
semanticscholar +1 more source
A method for the determination of creatine in blood serum with creatine phosphokinase
Clinica Chimica Acta, 1966Abstract A method is described for the determination of creatine in blood serum with creatine phosphokinase on the principles of that of Tanzer and Gilvarg 1 . Serum is treated with a solution of iodine and then protein is removed with barium hydroxide and zinc sulfate.
A.T. Milhorat, A.C. Kibrick
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Creatine and Creatine Deficiency Syndromes: Biochemical and Clinical Aspects
Pediatric Neurology, 2010Creatine deficiency syndromes, which have only recently been described, represent a group of inborn errors of creatine synthesis (L-arginine-glycine amidinotransferase deficiency and guanidinoacetate methyltransferase deficiency) and transport (creatine transporter deficiency). Patients with creatine deficiency syndromes present with mental retardation
Fahmi Nasrallah +2 more
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