Results 81 to 90 of about 332,672 (384)

Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]

, 2010
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey, Beeckman, Sam, Derave, Wim, Everaert, Inge   +3 more
core   +2 more sources

Creatine uptake regulates CD8 T cell antitumor immunity

Journal of Experimental Medicine, 2019
Di Biase et al. show for the first time that creatine acts as a “molecular battery” conserving bioenergy to power CD8 T cell activities; that creatine uptake is critical in supporting antitumor T cell immunity; and that creatine supplementation holds ...
S. Di Biase, Xiaoya Ma, Xi Wang, Jiaji Yu, Yu-Chen Wang, Drake J. Smith, Yang Zhou, Zhe Li, Y. J. Kim, N. Clarke, Angela To, Lili Yang   +11 more
semanticscholar   +1 more source

Wearable Systems of Reconfigurable Microneedle Electrode Array for Subcutaneous Multiplexed Recording of Myoelectric and Electrochemical Signals

Advanced Science, EarlyView.
A reconfigurable microneedle electrode array integrated system is developed for minimally invasive and transdermal monitoring of subcutaneous electromyography, reactive oxygen species, and pH values. By assembling discrete thumbtack‐shaped microneedles into an array, the system enables multi‐parameter detection with single‐microneedle resolution.
Zhengjie Liu, Chuanjie Yao, Xingyuan Xu, Xinshuo Huang, Shuang Huang, Shantao Zheng, Tao Zhang, Yan Li, Fanmao Liu, Yuxiang Wu, Jing Liu, Hui‐jiuan Chen, Xi Xie   +12 more
wiley   +1 more source

Potential advantages and disadvantages of using creatine supplements by professional volleyball players

Journal of Education, Health and Sport, 2018
Creatine, a peptide built from three amino acids: arginine, glycine and methionine, is one of the most popular diet supplements used by people who train not only strength sports but also other popular disciplines, including team sports, i.a.
Adrian Sieroń, Gabriela Kołodyńska, Paulina Rostojek   +2 more
doaj   +1 more source

Effectiveness of Creatine Supplementation on Aging Muscle and Bone: Focus on Falls Prevention and Inflammation

Journal of Clinical Medicine, 2019
Sarcopenia, defined as the age-related decrease in muscle mass, strength and physical performance, is associated with reduced bone mass and elevated low-grade inflammation.
D. Candow, Scott C. Forbes, P. Chilibeck, S. Cornish, J. Antonio, R. Kreider   +5 more
semanticscholar   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

The formation of glycocyamine in animal tissues [PDF]

, 1941
It was shown in preceding communications that glycocyamine is converted into creatine by surviving liver slices (1). Our findings indicated that the methylating agent is methionine or a derivative of methionine.
Borsook, Henry, Dubnoff, Jacob W.
core  

Creatine Kinase

Definitions, 2019
An enzyme complex that can reversibly convert ATP and creatine to phosphocreatine and ADP. Cytosolic creatine kinases are comprised of homodimers or heterodimers of creatine kinase B-type protein and creatine kinase M-type protein. Mitochondrial creatine
Y. Weerakkody, D. Bell
semanticscholar   +1 more source

ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy

Advanced Science, EarlyView.
The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li, Yi Liu, Kan Zhou, Lei‐Ming Cao, Guang‐Rui Wang, Jinmei Wu, Yi‐Fu Yu, Yao Xiao, Bing Liu, Qiuji Wu, Zhiyong Song, Lin‐Lin Bu   +11 more
wiley   +1 more source

On the role of the oxidation in the methylation of guanidoacetic acid [PDF]

, 1947
There are two, at least, methyl transfer reactions promoted by liver slices in vitro (2).
Borsook, Henry, Dubnoff, Jacob W.
core