Results 101 to 110 of about 162,921 (286)

m.10010T>C Mitochondrial Disease: A Case Report With Hypoparathyroidism and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mitochondria are essential intracellular organelles that play a critical role in cellular metabolism, including the regulation of intracellular calcium signaling. Advances in genomic sequencing have facilitated the identification of rare pathogenic mitochondrial DNA (mtDNA) genetic variants in patients with unexplained endocrine disorders.
Jacob Mohr, Anja Lisbeth Frederiksen, Morten Duno, Anne Pernille Hermann, Trine Maxel Juul, Simone Rask Nielsen   +5 more
wiley   +1 more source

Comparison of the effects of two types of acute weight loss program (2 and 4%) on the levels of creatine kinase and cardiac troponin enzymes

Fiyz̤, 2020
Background: One of the most common methods for assessing cardiac damage is the measurement of biological indicators related to heart tissue damage. This study aimed to compare the effects of two types of acute weight loss programs (2 and 4%) on the ...
Farzizade R, Bolboli L, Abravesh A, Nakhostin R   +3 more
doaj  

Correlation between Visfatin and Creatine Kinase Levels with Periodontal Health Status of Patients with Coronary Atherosclerosis and Chronic Periodontitis

Journal of Baghdad College of Dentistry, 2016
Background: Visfatin is a novel adipokine that mainly secreted by visceral adipose tissue, had an important role in inflammation and immune system. Creatine Kinase (CK) which is an enzyme that is involved in energy metabolism, found in large amounts in ...
Basma R. Omer, Maha Sh .Mahmood
doaj   +1 more source

Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy [PDF]

, 2010
Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Babu, Suresh, Mungli, Prakash, Shetty, Jeevan K   +2 more
core   +1 more source

Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. [PDF]

, 2012
BACKGROUND: Dengue is the most important vector-borne viral infection of man, with approximately 2 billion people living in areas at risk. Infection results in a range of manifestations from asymptomatic infection through to life-threatening shock and ...
Dung, Nguyen Thi Phuong, Farrar, Jeremy, Hien, Tran Tinh, Merson, Laura, Peeling, Rosanna, Simmons, Cameron, Tai, Luong Thi Hue, Truong, Nguyen Thanh, Van Hao, Nguyen, Van Vinh Chau, Nguyen, Whitehorn, James, Wills, Bridget, Wolbers, Marcel   +12 more
core   +1 more source

Novel MYL1 Intron Variant With Expanded Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington, Marie Balslev‐Harder, Thomas Krag, Thomas van Overeem Hansen, Camilla Bernt Wulff, Ulrik Lausten‐Thomsen, Tina Duelund Hjortshøj, Elsebet Østergaard   +7 more
wiley   +1 more source

Multiple prebiotic metals mediate translation. [PDF]

, 2018
Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C, Bray, Marcus S, Glass, Jennifer B, Haynes, Jay William, Hud, Nicholas V, Lenz, Timothy K, Petrov, Anton S, Reddi, Amit R, Williams, Loren Dean   +8 more
core   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Dose Dependent Effects of Corticosterone of Proliferation and Differentiation in Chick Myoblasts

The Journal of Poultry Science, 2001
The effect of corticosterone (CTC) at low and high concentrations on proliferation and differentiation was studied in chick myoblasts. Chick myoblasts were incubated with low (3ng/ml) and high (30ng/ml) levels of CTC.
Kazue Machida, Katumi Konya, Kazuki Nakashima, Akira Ohtsuka, Kunioki Hayashi   +4 more
doaj   +1 more source

Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training [PDF]

, 2008
Purpose of Review: Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging.
Cribb, Paul J, Hayes, Alan
core   +1 more source