Comparing Theories for the Maintenance of Late LTP and Long-Term Memory: Computational Analysis of the Roles of Kinase Feedback Pathways and Synaptic Reactivation [PDF]
arXiv, 2020 How can memories be maintained from days to a lifetime, given turnover of proteins that underlie expression of long-term synaptic potentiation (LTP)? One likely solution relies on synaptic positive feedback loops, prominently including persistent activation of CaM kinase II (CaMKII) and self-activated synthesis of protein kinase M zeta (PKM).
arxiv
Comparison of four different algorithms for the calculation of radioimmunoassay standard curves [PDF]
, 1980 Peer ...
Herndl, R. +2 more
core +2 more sources
Effect of acute and chronic coenzyme Q10 supplementation on creatine kinase after exhaustive aerobic activity [PDF]
International Journal of Biomedicine and Public Health, 2018 Introduction: Fatigue and muscle ache, is a common and prevalent experience after physical activity, especially exhausting activities. The purpose of this study was to investigate the acute and chronic effects of supplementation of coenzyme Q10 on ...
Parvaneh Valadbeigi +2 more
doaj
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Cardiopulmonary bypass (CPB) is the standard approach for coronary artery bypass grafting (CABG) in advanced ischaemic cardiomyopathy. Microaxial pump support has been envisioned to allow for beating‐heart CABG without CPB (MPCAB), thereby avoiding CPB‐inherent complications.
Anna Kathrin Assmann +5 more
wiley +1 more source
An unexpected and devastating adverse event of dasatinib: Rhabdomyolysis
Leukemia Research Reports, 2016 We, herein, describe a 52-year-old male whom developed rhabdomyolysis and acute renal failure likely related to dasatinib shortly after the administration of treatment.
Burak Uz, Ilhan Dolasik
doaj +1 more source
The Thiol Groups and Sub-unit Structure of Creatine Kinase [PDF]
, 1967 Peter M. Bayley, A. R. Thomson
openalex +1 more source
The combinational effect of cardiac and biochemical markers in diabetic patients with cardiovascular disease [PDF]
, 2011 Background: Clinicopathological correlations, as well as several angiographic studies, suggest that diabetic patients have more extensive atherosclerotic disease, affecting the coronary arteries in particular.
Palanisamy Pasupathi, YY Rao, Farook J, Sathiyamoorthy Subramaniyam, Babu Shankar Ponnusha, Athimoolam Ambika, Int J Cur Bio Med Sci.
core
A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors. [PDF]
, 2016 Purpose TAK-733, an investigational, selective, allosteric MEK1/2 inhibitor, has demonstrated antitumor effects against multiple cancer cell lines and xenograft models. This first-in-human study investigated TAK-733 in patients with solid tumors. Methods
Adjei, Alex A +11 more
core +1 more source
Van Tıp Dergisi, 2019 INTRODUCTION: The aim of this study was to evaluate the effect of the myalgia observed as a side effect of isotretinoin used for severe and treatment-resistant moderate acne on patient quality of life and to investigate the relationship between serum ...
Ebru Karagun
doaj +1 more source