Results 81 to 90 of about 1,019,575 (429)

Positional information readout in $Ca^{2+}$ signaling [PDF]

open access: yesPhys. Rev. Lett. 123, 058102 (2019), 2017
Living cells respond to spatial signals. Signal transmission to the cell interior often involves the release of second messengers like $Ca^{2+}$ . They will eventually trigger a physiological response by activating kinases that in turn activate target proteins through phosphorylation. Here, we investigate theoretically how positional information can be
arxiv   +1 more source

Changes in power assessed by the Wingate anaerobic test following downhill running [PDF]

open access: yes, 2007
Few studies have examined the effects of eccentric exercise-induced muscle damage on power despite power being a key performance variable in a number of sporting events.
Nosaka, K., Nottle, C.
core   +3 more sources

Interference by creatine with determination of serum creatine kinase.

open access: yesClinical Chemistry, 1976
We assayed creatine kinase (EC 2.7.3.2) activity in normal serum and in specimens obtained from patients with high serum creatinine by four automated methods: (a) the Technicon SMA 12/60, (b) the Technicon AutoAnalyzer Ii, (c) the Abbott Bichromatic Analyzer, and ( the Aminco Rotochem. Activity blanks were assayed with the AutoAnalyzer II system.
D J Adler, H M Goldschmidt, R W Lent
openaire   +3 more sources

Creatine-Kinase- and Exercise-Related Muscle Damage Implications for Muscle Performance and Recovery

open access: yesJournal of Nutrition and Metabolism, 2012
The appearance of creatine kinase (CK) in blood has been generally considered to be an indirect marker of muscle damage, particularly for diagnosis of medical conditions such as myocardial infarction, muscular dystrophy, and cerebral diseases.
Marianne F. Baird   +3 more
semanticscholar   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

Stilbene‐based derivatives as potential inhibitors of trimethylamine (TMA)‐lyase affect gut microbiota in coronary heart disease

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 93-100, January 2023., 2023
Docking results showed Resveratroloside had the highest Vina score, indicating that it was the most active and might be employed as a lead molecule for further structural modification. The possible action process of TMA‐Lyase lead compound was described, which further affects the occurrence and development of CHD.
Jincai Li   +3 more
wiley   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

open access: yes, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala   +2 more
core   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

open access: yesAdvanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen   +5 more
wiley   +1 more source

Evaluation of the acute toxicity and 28‐days subacute toxicity of the alcoholic extract from Ganoderma leucocontextum

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 434-442, January 2023., 2023
The toxicity of Ganoderma leucocontextum was evaluated for the first time. No toxicological changes were found in acute and subacute toxicity test. Ganoderma leucocontextum showed a good safety profile in animal study. Abstract Ganoderma leucocontextum is a well‐known traditional medicine in Tibet Autonomous Region, which has benefits, such as anti ...
Shizhan Deng   +4 more
wiley   +1 more source

Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study [PDF]

open access: yes, 2012
Background: It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes soreness and discomfort. Branched-chain amino acid (BCAA) supplementation has been shown to increase protein synthesis and decrease muscle ...
Bell, Phillip   +5 more
core   +3 more sources

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