Results 121 to 130 of about 867,384 (315)

Prediction of Chronic Kidney Disease Using Deep Neural Network [PDF]

open access: yesarXiv, 2020
Deep neural Network (DNN) is becoming a focal point in Machine Learning research. Its application is penetrating into different fields and solving intricate and complex problems. DNN is now been applied in health image processing to detect various ailment such as cancer and diabetes.
arxiv  

Human urinary mutagenicity after wood smoke exposure during traditional temazcal use. [PDF]

open access: yes, 2014
In Central America, the traditional temazcales or wood-fired steam baths, commonly used by many Native American populations, are often heated by wood fires with little ventilation, and this use results in high wood smoke exposure.
HOLLAND, Nina   +8 more
core   +3 more sources

Study of Serum urea and Creatinine in Diabetic and non-diabetic patients in in a tertiary teaching hospital

open access: yesThe Journal of medical research, 2016
Introduction: Diabetes is on the rise worldwide and India has more number of diabetics with more than 60 million people diagnosed to suffer from the disease in 2013. Approximately 20% to 30% of all diabetics will develop evidence of nephropathy, although
S. Bamanikar, A. Bamanikar, A. Arora
semanticscholar   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare   +7 more
wiley   +1 more source

The hydrolysis of phosphocreatine and the origin of urinary creatinine [PDF]

open access: yes, 1947
Shaffer (1), Myers and Fine (2), and Hahn and Meyer (3) adduced evidence that muscle creatine is the precursor of urinary creatinine. This was questioned by Chanutin and Kinard (4) but was conclusively proved by Bloch, Schoenheimer, and Rittenberg (5, 6)
Borsook, Henry, Dubnoff, Jacob W.
core  

Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]

open access: yes, 1989
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt   +72 more
core   +1 more source

Salivary creatinine and urea analysis in patients with chronic kidney disease: a case control study

open access: yesBMC Nephrology, 2016
BackgroundMany metabolic changes develop in patients with chronic kidney disease which often necessitate frequent biochemical analysis of blood. Saliva analysis as an alternative to blood has many advantages.
T. J. Lasisi, Y. Raji, B. Salako
semanticscholar   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou   +7 more
wiley   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

open access: yesAdvanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang   +12 more
wiley   +1 more source

Use of cystatin C to inform metformin eligibility among adult veterans with diabetes. [PDF]

open access: yes, 2016
AimsRecommendations for metformin use are dependent on eGFR category: eGFR >45 ml/min/1.73 m2 - "first-line agent"; eGFR 30-44 - "use with caution"; eGFR<30 - "do not use".
Grunfeld, Carl   +5 more
core   +2 more sources

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