Renal and Hepatic Dysfunction in Malaria Patients in Minna, North Central Nigeria [PDF]
Information on kidney and liver involvement in malaria in Africa is still very scanty. Kidney and liver functions were assessed in 70 malaria patients using serum levels of creatinine and urea and urinary protein levels as test indicators of kidney ...
Ogbadoyi, EO, Tsado, RD
core +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior+5 more
wiley +1 more source
Blood urea nitrogen as a predictor of mortality in myocardial infarction [PDF]
INTRODUCTION Blood urea nitrogen and creatinine levels are routine laboratory tests for evaluating renal function. Renal dysfunction has been related to worse prognosis of cardiovascular diseases.
Liong Boy Kurniawan+4 more
doaj
Objetivou-se avaliar o efeito de quatro níveis de uréia na ração (0; 0,65; 1,3 e 1,95% na matéria seca - MS) sobre pH e amônia ruminais, concentração plasmática de uréia, excreção fracional de uréia e excreções de uréia e creatinina, bem como avaliar as ...
Luciana Navajas Rennó+6 more
doaj +1 more source
Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]
Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska+8 more
core +3 more sources
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald+74 more
wiley +1 more source
Environmental Tobacco Smoke Exposure in Relation to Family Characteristics, Stressors and Chemical Co-Exposures in California Girls. [PDF]
Childhood environmental tobacco smoke (ETS) exposure is a risk factor for adverse health outcomes and may disproportionately burden lower socioeconomic status groups, exacerbating health disparities.
Dobraca, Dina+5 more
core +1 more source
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung+6 more
wiley +1 more source
Urinary IL-18 as an early marker for acute kidney injury in snake bite [PDF]
Background: Several biomarkers have been thrown into limelight to be an early predictor of Acute Kidney Injury (AKI). Aim and Objectives:To establish the relation between Urinary IL-18 (UIL-18) and AKI and the reliability for use as early markers in the ...
Suram Vasanth Kumar +3 more
doaj
Environmental Chemicals in Urine and Blood: Improving Methods for Creatinine and Lipid Adjustment
Background Investigators measuring exposure biomarkers in urine typically adjust for creatinine to account for dilution-dependent sample variation in urine concentrations.
K. O’Brien+3 more
semanticscholar +1 more source