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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Determination of Plasmalogen Molecular Species in Hen Eggs
(1) Background: Plasmalogens are vinyl ether-type glycerophospholipids that are characteristically distributed in neural tissues and are significantly reduced in the brains of individuals with dementia compared to those in healthy subjects, suggesting a ...
Taiki Miyazawa +3 more
doaj +1 more source
Creation Of The Universe [PDF]
Creation of the Universe traces the development of the Big Bang theory, from the expansion of the universe to quantum cosmology, from the formation of large scale structure to the physics of the Planck era. Fang Li Zhi, a leading Chinese astrophysicist and Li Shu Xian (co-author and wife) trace the advances in cosmology and recount experiences made by ...
Fang Li Zhi, Li Shu Xian
openaire +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Job Creation and Destruction in Northern Ireland - 1973-1993 [PDF]
Job creation and destruction estimates are made for Northern Ireland manufacturing using the ARD database. International comparisons suggest job creation and destruction rates in Northern Ireland were below those elsewhere. Job turnover rates exhibit the
Stephen Roper
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The order of creation : the conflict between Genesis and geology /
Dawn of creation and of worship / W.E. Gladstone -- The interpreters of Genesis and the interpreters of nature / T.H. Huxley -- Postscript to solar myths / Max Müller -- Proem to Genesis / W.E.
Gladstone, W. E. (William Ewart), 1809-1898.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Servitization strategies and Co-creation
Purpose: This research aims at investigating the moderating role of co-creation in the implementation of servitization strategies in the pharmaceutical industry.
Frias, D. +3 more
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

