Results 91 to 100 of about 2,585,168 (250)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Entrepreneurship, Job Creation, and Wage Growth [PDF]
This paper analyses the importance of entrepreneurs for job creation and wage growth. Relying on unique data that cover all establishments, firms and individuals in the Danish private sector, we are able to distil a number of different subsets from the ...
Nikolaj Malchow-Møller +2 more
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The Beginning and Before: Interpreting Creation in Paul and Philo [PDF]
, 2010 God’s creative activity in the beginning is important to Paul. Yet Paul’s care for and interpretation of it is often unrecognized, occasionally denied, typically left underdeveloped, and sometimes interpreted wrongly.
WORTHINGTON, JONATHAN,DAVID +1 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Exploring co-creation networks : creating balanced centricity within a public transport service [PDF]
, 2011 This presentation looks at exploring co-creation networks and creating balanced centricity within a public transport ...
Jaakkola, Elina, Alexander, Matthew
core +2 more sources
The order of creation : the conflict between Genesis and geology /
, 1885 Dawn of creation and of worship / W.E. Gladstone -- The interpreters of Genesis and the interpreters of nature / T.H. Huxley -- Postscript to solar myths / Max Müller -- Proem to Genesis / W.E.
Gladstone, W. E. (William Ewart), 1809-1898.
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Job creation and job destruction in the EU agriculture [PDF]
This is the first paper to study job creation and destruction in EU agriculture. We disaggregate employment patterns and job flows into detailed intra-sectoral labour adjustment dynamics based on farm level panel observations from 1989-2006. We find that:
Dries, Liesbeth +2 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source