Results 81 to 90 of about 6,504,570 (342)

Gene profiles and mutations in the development of cataracts in the ICR rat model of hereditary cataracts

Scientific Reports, 2023
Cataracts are opacifications of the lens that cause loss of visual acuity and ultimately of eyesight. Age-related cataract develops in most elderly people, but the mechanisms of cataract onset are incompletely understood.
Masaru Takashima, Kei Taniguchi, Masaya Nagaya, Shunki Yamamura, Yoshihiro Takamura, Masaru Inatani, Masaya Oki   +6 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Growing highly ordered Pt and Mn bimetallic single atomic layers over graphdiyne

Nature Communications
Controlling the precise growth of atoms is necessary to achieve manipulation of atomic composition and atomic position, regulation of electronic structure, and an understanding of reactions at the atomic level.
Zhiqiang Zheng, Lu Qi, Xiaoyu Luan, Shuya Zhao, Yurui Xue, Yuliang Li   +5 more
doaj   +1 more source

Characterizing quantumness via entanglement creation

, 2011
In [M. Piani et al., arXiv:1103.4032 (2011)] an activation protocol was introduced which maps the general non-classical (multipartite) correlations between given systems into bipartite entanglement between the systems and local ancillae by means of a ...
Datta A., GERARDO ADESSO, JOHN CALSAMIGLIA, MARCO PIANI, PAWEŁ HORODECKI, Plenio M. B., SEVAG GHARIBIAN   +6 more
core   +1 more source

Thermodynamic constraints on matter creation models

, 2020
Entropy is a fundamental concept from Thermodynamics and it can be used to study models on context of Creation Cold Dark Matter (CCDM). From conditions on the first ($\dot{S}\geq0$)\footnote{Throughout the present work we will use dots to indicate time ...
Jesus, J. F., Valentim, R.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An agile co-creation process for digital servitization: A micro-service innovation approach

, 2020
In this paper, we explore how manufacturing firms and their customers co-create digital service innovations in an attempt to address the digitalization paradox.
D. Sjödin, V. Parida, Marko Kohtamäki, J. Wincent   +3 more
semanticscholar   +1 more source