Results 71 to 80 of about 5,782,070 (237)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Case studies (Swinburne Commons)

open access: yes, 2016
Swinburne Commons is the centralised service for the management and distribution of digital media at Swinburne University. This video describes three digital media projects at Swinburne that we have been involved with: 1) EndNote tutorials; 2) MathsCasts
Swinburne Commons
core   +1 more source

Creative Commons Australia and Organization for Transformative Works submission to the Australian Government’s online copyright infringement discussion paper [PDF]

open access: yes, 2014
This submission focuses on the adverse effects that the Government’s proposals are likely to have on the legitimate use of copyright works. Copyright exists to support the production of new expression.
Suzor, Nicolas P., Tushnet, Rebecca
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Building an Australasian Commons : Creative Commons case studies vol. 1 [PDF]

open access: yes, 2008
A collection of 60 case studies of the use of Creative Commons licensing in different sectors, including: music, social activism, film, visual arts, collecting, government, publishing and ...
Cobcroft, Rachel S.   +2 more
core   +1 more source

Review of Byline of Hope: Collected Newspaper and Magazine Writing of Helen Keller

open access: yesDisability Studies Quarterly, 2017
No abstract available. © 2017 Marcum. All rights reserved. By author request, this article is excluded from Creative Commons licensing.
Andrew Marcum
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Copyleft e licenças criativas de uso de informação na sociedade da informação

open access: yesCiência da Informação, 2008
Neste trabalho se discutem algumas licenças criativas de uso de informação: Free Document Licenses (FDL) e Creative Commons (CC). As formas colaborativas de produção, disseminação e uso de informação, particularmente aquelas que usam a Internet, requerem
Clovis Ricardo Montenegro de Lima   +1 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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