Results 51 to 60 of about 281,244 (243)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Creative Commons — the other way? [PDF]
Learned Publishing, 2007 ABSTRACTOn 9 Mar 2006, the District Court of Amsterdam upheld the Creative Commons (CC) licence in relation to photographs made available for the public on an online sharing website, but subject to a Creative Commons licence. This is the first known court decision involving a Creative Common licence, not only in the European Union, but worldwide, that ...
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Dietrich Schulte-Frohlinde (1924 – 2015)
Croatica Chemica Acta, 2016 Professor Dietrich Schulte-Frohlinde, a distinguished German chemist with long-time relationships to Croatian scientists (e.g. S. Ašperger, M. Randić, J. N. Herak, A. Graovac, I. Kraljić), and this Journal, passed away on Oct 1st, 2015 in Chevy Chase MD,
Leo Klasinc, Hans Güsten
doaj +1 more source
(Free) Creative Commons content on the internet is not so free after all: The pitfalls and details of copyright laws and licenses. [PDF]
EMBO Rep, 2023 Roder-Hießerich V.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
F1000Research, 2015 The Global Food Safety Partnership (GFSP) is a public/private partnership established through the World Bank to improve food safety systems through a globally coordinated and locally-driven approach.
Paul Stacey +2 more
doaj +1 more source
, 2021 Im KONDE-Projekt, das aus Hochschulraumstrukturmitteln finanziert wird, beschäftigten sich sieben universitäre Partner und drei weitere Einrichtungen aus unterschiedlichen Blickwinkeln mit theoretischen und praktischen Aspekten der Digitalen Edition. Ein Outcome des Projektes stellt das Weißbuch dar, welches über 200 Artikel zum Thema Digitale Edition ...
openaire +1 more source