Results 111 to 120 of about 1,367,790 (258)

TAS Creative Industry Council - Workshop Invitation.pdf

open access: yes, 2015
Invitation to attend an Alliance Building Workshop: Tasmania: Australia's future creative capital. Forum aimed at discussing a proposal to start a 'Tasmanian Creative Council' - to represent and advocate the interests of all creative enterprises and ...
Creative Industries Innovation Centre
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Creativity in drama : explanations and explorations

open access: yes, 2010
Educational rhetoric often includes calls for teachers to promote creativity in the classroom. The concept of creativity is not often unpacked or explored, especially in relation to specific curriculum areas. This article seeks to explore what creativity
Susan Davis (8992994), Davis, Susan.
core  

Improvisation, process drama and dramatic art [PDF]

open access: yes, 1991
This paper re-conceptualises the notion of improvisation as it has developed in schools since the 1960s. It outlines the theoretical case for naming the distinctive improvisational practice that has emerged in schools - namely Process Drama.
Haseman, Bradley C.
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Expanding enabling places theory through land-based cultural learning with indigenous men

open access: yesWellbeing, Space and Society
Urban Indigenous men often lack opportunities to connect with the land and their culture. In this article, we report on a community-based participatory research project with urban Indigenous men in a land-based traditional drum-making program in Manitoba,
Candice Waddell-Henowitch   +5 more
doaj   +1 more source

An investigation into the space where drama education and dramatherapy meet. What does this mean in conceptual and practical terms for practitioner and participant? [PDF]

open access: yes
The aim of this research is to explore the space between drama education and dramatherapy as practised in the UK and find a way of describing it. I begin by looking at five areas relevant to both professions: theatre and anthropology, theatre and ...
Holmwood, Clive
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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