Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Romanian Framework for Creative Industries and Virtual Incubators [PDF]
In order to promote creative industries in Romania, as partners of VIC, we propose an application project related to a personalized guide of South-East Region of Romania as a result of creative firms cooperation.
Victor Ionescu
core +1 more source
Developing the rural creative economy 'from below': exploring practices of market-building amongst creative entrepreneurs in rural and remote Scotland [PDF]
, 2016 The article draws on material gathered as part of three research projects, the first, ‘Supporting Creative Business’ was funded by the UK Arts and Humanities Research Council, the second, ‘Towards a model of support for the rural creative industries’ was
Munro, Ealasaid
core +1 more source
Financing the cultural and creative industries through crowdfunding: the role of national cultural dimensions and policies. [PDF]
J Cult Econ (Dordr), 2023 Cicchiello AF, Gallo S, Monferrà S.
europepmc +1 more source
Behind the ‘creative destruction’ of human diets: an analysis of the structure and dynamics of the ultra-processed food manufacturing industry and implications for public health [PDF]
, 2023 Oli Williams, Phillip Baker, Gary Sacks
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Embodied Knowledge Transfer Comparing inter-firm labor mobility in the music industry and manufacturing industries [PDF]
This paper adds new knowledge to the phenomenon of transferring embodied knowledge through labor mobility by means of a comparative study of the entertainment and manufacturing industries.
Lars Frederiksen, Silvia Rita Sedita
core
Innovation and diversity in the digital cultural and creative industries. [PDF]
J Cult Econ (Dordr), 2021 Snowball J, Tarentaal D, Sapsed J.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source