Results 141 to 150 of about 3,602,415 (283)

The Quest for Inner Freedom: An Artist’s Perspective

open access: yesReligions
The article examines my artist’s struggle for inner freedom in practice-led artistic research through the medium of drawing. This inquiry, framed within a Catholic perspective, investigates the idea that the quest for inner freedom is vital for artistic ...
Ivana Gagić Kičinbači
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Can medium-sized cities become Creative Cities? Discussing the cases of three Central and Western European cities [PDF]

open access: yes, 2018
This paper aims to explore the concept of Creative City from the points of view of three medium-sized cities in Central and Western Europe: Birmingham (UK), Leipzig (Germany) and Poznań (Poland).
Chapain, Caroline   +2 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

PERAN SUTRADARA DALAM PROSES KREATIF PRODUKSI FILM FIKSI PENDEK BERJUDUL 5 MIN 1 [PDF]

open access: yes
ION Marzuki Anwar, 201810040311390 The Role of the Director in the Creative Process of Short Fiction Film Production Titled 5 Min 1, 2024, Communication Science Study Program, Faculty of Social and Political Sciences, Muhammadiyah University of Malang.
Anwar, Marzuki
core  

Conformity, deformity and reformity [PDF]

open access: yes, 2015
In any given field of artistic practice, practitioners position themselves—or find themselves positioned—according to interests and allegiances with specific movements, genres, and traditions. Selecting particular frameworks through which to approach the
Brown, Michael, Wilson, Chris
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

From Talent to Creative City: Towards a conceptual framework [PDF]

open access: yes
The creative class approach (Florida, 2002b) has led to many developments. Therefore, measurement of creativity (Chantelot, 2010), economic influence of creative people in urban (Marlet & Van Woerkens, 2007) and rural (McGranahan & Wojan, 2007 ...
Peres Stephanie   +2 more
core  

Home - About - Disclaimer - Privacy