Results 91 to 100 of about 1,391,241 (279)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Kemampuan Berpikir Kreatif Siswa Melalui Creative Problem Solving [PDF]

open access: yes, 2016
Creative thinking ability is the one of important things in mathematics lesson. In developing such creative thinking ability, teachers must be good at giving ideas and issues which are relatively different from before, so that we can find something new ...
Afriansyah, E. A. (Ekasatya)   +1 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Mathematical Creative Thinking and Student Self-Confidence in the Challenge-Based Learning Approach

open access: yesJournal of Research and Advances in Mathematics Education, 2018
The new curriculum (K13) requires a teacher to develop students’ ability in order to learn and fully understand Mathematics. The important abilities needed for a student in understanding Mathematics are the creative thinking and self-confidence.
Hayatun Nufus   +2 more
doaj   +1 more source

Kontribusi Laboratorium Kimia dan Sikap Siswa terhadap Pemanfaatan Laboratorium terhadap Keterampilan Berpikir Kritis dan Kreatif [PDF]

open access: yes, 2017
The purpose of this research is to analyze the contribution of chemistry laboratory and student attitudes toward the utilization of chemistry laboratory toward critical and creative thinking skill.
Nursa\u27adah, F. P. (Fatwa)   +1 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Developing the Management Competencies for Getting a Competitive Position in the Organic Food Market [PDF]

open access: yes
Although almost any conference tackles the issue of organic foods, we consider that this article does not fit into normal patterns of research. Our paper proposes a complex analysis in the field of organic food products.
Marian NASTASE   +2 more
core  

Functional System of Creative Thinking [PDF]

open access: yes, 2016
In the article on the basis of electroencephalographic and psychological indicators the concept the mechanism of creative thinking was formulated. Creative thinking as a process involves operating images and searching similar tasks in memory (mental ...
Abramchuk, Olha M.   +17 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The Role of Social Support to Foster Creative Thinking of Vocational Students In University: Mediating Effect of Creative Self-Efficacys

open access: yesQubahan Academic Journal
Creative thinking skills have become one of the skills needed in the future. Many studies highlight the critical role of social support in forming students' creative thinking skills. However, the existing literature is still unclear about the structural
Ida Nugroho Saputro   +3 more
doaj   +1 more source

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