Results 101 to 110 of about 1,403,002 (296)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Mathematical Creative Thinking and Student Self-Confidence in the Challenge-Based Learning Approach

Journal of Research and Advances in Mathematics Education, 2018
The new curriculum (K13) requires a teacher to develop students’ ability in order to learn and fully understand Mathematics. The important abilities needed for a student in understanding Mathematics are the creative thinking and self-confidence.
Hayatun Nufus, Muhammad Duskri, Bahrun Bahrun   +2 more
doaj   +1 more source

Functional System of Creative Thinking [PDF]

, 2016
In the article on the basis of electroencephalographic and psychological indicators the concept the mechanism of creative thinking was formulated. Creative thinking as a process involves operating images and searching similar tasks in memory (mental ...
Abramchuk, Olha M., Dmytrotsa, Olena R., Kachynska, Tetiana V., Kotsan, Ihor Ya., Kozachuk, Nataliia O., Poruchynska, Tetiana F., Poruchynskyi, Andrii I., Shvarts, Liudmyla O., Zhuravlov, Oleksandr A., Абрамчук, Ольга Миколаївна, Дмитроца, Олена Романівна, Журавльов, Олександр Анатолійович, Качинська, Тетяна Володимирівна, Козачук, Наталія Олександрівна, Коцан, Ігор Ярославович, Поручинська, Тетяна Федорівна, Поручинський, Андрій Іванович, Шварц, Людмила Олексіївна   +17 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Role of Social Support to Foster Creative Thinking of Vocational Students In University: Mediating Effect of Creative Self-Efficacys

Qubahan Academic Journal
Creative thinking skills have become one of the skills needed in the future. Many studies highlight the critical role of social support in forming students' creative thinking skills. However, the existing literature is still unclear about the structural
Ida Nugroho Saputro, Sukatiman Sukatiman , Abdul Haris Setiawan , Ayu Intan Sari   +3 more
doaj   +1 more source

Pengaruh Pendekatan Pembelajaran Berbasis Masalah terhadap Kemampuan dan Disposisi Berpikir Kritis dan Kreatif Matematis Siswa Sekolah Menengah Atas. [PDF]

, 2015
Masalah yang dikaji dalam penelitian ini adalah bagaimana pengaruh pendekatan pembelajaran berbasis masalah terhadap kemampuan berpikir kritis dan kreatif matematis, serta disposisi berpikir kritis dan kreatif matematis pada siswa SMA.
Widyatningtyas, Reviandri
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

DEVELOPING TEACHER PERFORMANCES TO IMPROVING STUDENTS CREATIVE THINKING CAPABILITIES IN MATHEMATICS [PDF]

, 2014
Teacher performances to improving students creative thinking is still weakness. The research report finds out those 130 elementary teachers could not impress and direct students developing students’ creative thinking.
Tatag, SISWONO
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

آنچه کتابداران دانشگاهی باید در مورد تفکر خلاق بدانند [PDF]

کتابداری و اطلاع‌رسانی, 2009
کتابداران دانشگاهی نیازمند کشف خلاقیت فردی هستند.  تفکر خلاق نوعی مهارت مغفول مانده برای حل مسئله است که می‌توان آن را آموخت و در هر موقعیتی به کار گرفت. این مقاله توضیح می دهد که چگونه کتابداران می توانند تفکر خلاق  خود را بشناسند، آن را توسعه دهند و از
جان ای السن, مینا طلاکوب   +1 more
doaj