Results 71 to 80 of about 1,395,541 (300)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The influence of thinking styles and gender on students' creative thinking abilities in physical education

open access: yesEdu Sportivo
Background: Modern developments require Generation Z to be able to face future challenges that cannot be predicted. Research Objectives: The purpose of this study is to investigate how thinking styles and gender can develop creative thinking skills in ...
Dupri   +3 more
doaj   +1 more source

The Role of Metacognitive Components in Creative Thinking

open access: yesFrontiers in Psychology, 2019
Metacognition refers to the knowledge and regulation of one’s own cognitive processes, which has been regarded as a critical component of creative thinking.
Xiaoyu Jia, Weijian Li, Liren Cao
doaj   +1 more source

The Butterfly Effect: Creative Sustainable Design Solutions through Systems thinking [PDF]

open access: yes, 2007
FAIM: Intelligent Manufacturing now, Limerick ...
Hadfield, Mark, McMahon, M.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Logical Thinking/Creative Thinking

open access: yes, 2014
AbstractIn this chapter, creativity will be examined and structured from the perspective of transaction. Just as in the previous chapters, the enhancement of the creative thinking process and activity will be studied by applying the methodology of managing transaction costs.
openaire   +1 more source

The Level of Students’ Creative thinking Skills in Solving Probability Problem through Scientific Approach [PDF]

open access: yes, 2018
Mathematics students' creative thinking skills through scientific approach. This study employed descriptive study with qualitative approach and the data collection employed test to determine the levels of students' creative thinking skills.
Herlina, V. Y. (Vilda)   +2 more
core  

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