Results 121 to 130 of about 25,654 (252)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Are Adolescents with Higher Openness More Creative Under Stress? The Mediating Role of Stress Perception and Cognitive Flexibility. [PDF]
J IntellWang Y, Liu J, Li Y, Duan H.
europepmc +1 more source
CREATIVITY OF STUDENT AS UNIVERSAL COGNITIVE CREATIVE ABILITY
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015 In the article the features of organization of cognitive activity are presented on the basis of креативного approach in institution of higher learning of culture. The special value in the creative educating and education is acquired by modern pedagogical technologies, methodologies, forms, methods and facilities.
openaire +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A Framework to Assess Food Insecurity Responses Among Colleges and Universities. [PDF]
NutrientsGonzalez SR, Thornton K, Powers A.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The impact of short video addiction on the creativity of college students: the mediating role of intrinsic motivation and innovative self-efficacy. [PDF]
Front PsycholSha P, Gu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Environmental health in crisis-who do we want to be? [PDF]
J Expo Sci Environ EpidemiolClougherty JE.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source