Results 71 to 80 of about 25,654 (252)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Prospects of International Cooperation in Training of Specialists in the Field of Art and Culture
Высшее образование в России, 2018 The article presents the experience of the international activities of Khabarovsk State Institute of Culture and partner universities of the People’s Republic of China in the training of specialists for the sphere of culture and art.
E. V. Savelova
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические наукиThe relevance of the research is explained by the existing contradiction between the objective need of society, the state, and the Armed Forces of the Russian Federation for military specialists with developed intellectual and creative potential who are ...
Alena E. Alekseenko
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Enhancing creativity through a problem-based design thinking project in higher education
Cogent EducationThe study explored the impacts of the two-day Living LAB urban regeneration idea camp, which enhanced college students’ divergent thinking skills and creative self-efficacy.
Hyunjun Choi, Hyowon Kim, Nooree Kim
doaj +1 more source
Identification of creative investment in global economy [PDF]
International Economic Policy, 2016 This article is devoted to the creativization process of economic development under the conditions of the transformation of forms and methods of global competition.
Dmytro Lukianenko +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source