Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Participation in a Physician Creative Writing Community: 15-Year Program Survey Outcomes at an Academic Medical Center. [PDF]
J Gen Intern MedPien J +5 more
europepmc +1 more source
Use of Creative Writing to Develop a Semantic Differential Tool for Assessing Soundscapes. [PDF]
Front Psychol, 2018 Welch D +4 more
europepmc +1 more source
Creativity, Structure, and Expression in Creative Writing: Evidence from EFL Music and Sports Majors
Jie Qin, Meitong Zhou
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
REWRITALIZE your recovery: a study protocol for a randomised controlled trial (RCT) examining the effectiveness of the new recovery-oriented creative writing group intervention REWRITALIZE for people with severe mental illness. [PDF]
BMC PsychiatryHenningsson S +7 more
europepmc +1 more source
Is training in creative writing a feasible treatment adjunct for clients suffering from chronic alcohol-use disorder? [PDF]
Nordisk Alkohol Nark, 2017 Hellum R, Jensen S, Nielsen A.
europepmc +1 more source
Creative Writing: The Wilderness is Yet the Garden
, 2023 Pier Giorgio Di Cicco
openalex +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Combining creative writing and narrative analysis to deliver new insights into the impact of pulmonary hypertension. [PDF]
BMJ Open Respir Res, 2017 Goddard JC +7 more
europepmc +1 more source