Results 91 to 100 of about 225,562 (293)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Improving the translation of search strategies using the Polyglot Search Translator: a randomised controlled trial

open access: yes
<b>External Organisations</b><br/>Gold Coast University Hospital; Southern Cross University; Queensland University of Technology; University of Queensland; Australian Catholic University; University of Adelaide; University of Newcastle;

core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Avaliação dos Atributos dos Programas de Compliance para o desenvolvimento do Sistema Blockchain no Contexto das organizações

open access: yesFronteiras da Representação do Conhecimento
Compliance programs have legal, administrative and technological attributes that help organizations find solutions related to strategy, management and organizational governance.
Henrique Rodrigues Lelis   +2 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Matter of Style: Community Building between Seduction and Indirect Communication

open access: yesSocial Sciences
Diverging from studies that categorize influencers solely as advertising figures subject to interpretation within marketing frameworks, this research employs an extensive netnography to examine influencers through the lens of cultural production theory ...
Tito Vagni
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Summary of raw data for median ED length of stay (measured in hours), with breakdown by Australasian Triage Score (ATS) categories: Highest acuity (ATS 1&2) attendances; Moderate Acuity (ATS 3) attendances; and lower acuity (ATS 4&5) attendances.

open access: yes
<b>Associated Persons</b><br/>Roberto Forero (Creator); Peter Carl Sprivulis (Creator)Wing Nicola Man (Creator); Mohammed Mohsin (Creator); Sam Toloo (Creator); Gerard Fitzgerald (Creator); Sally Mccarthy (Creator); Ken Hillman (Creator)

core   +1 more source

Analysis of Switched-Rigid Floating Oscillator

open access: yesShock and Vibration, 2009
In explicit finite element simulations, a technique called deformable-to-rigid (D2R) switching is used routinely to reduce the computation time. Using the D2R option, the deformable parts in the model can be switched to rigid and reverted back to ...
Prabhakar R. Marur
doaj   +1 more source

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