Results 131 to 140 of about 33,277 (314)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Computational simulation of probabilistic lifetime strength for aerospace materials subjected to high temperature, mechanical fatigue, creep and thermal fatigue [PDF]

This report presents the results of a fourth year effort of a research program, conducted for NASA-LeRC by the University of Texas at San Antonio (UTSA).
Bast, Callie C., Boyce, Lola, Trimble, Greg A.   +2 more
core   +1 more source

Fluid-structure interaction on the combustion instability [PDF]

, 2012
The multi-domain problem, the limit cycle behaviour of unstable oscillations in the LIMOUSINE model combustor has been investigated by numerical and experimental studies.
Altunlu, A.C., Boer, A de, Hoogt, P.J.M. van der, Kok, J.B.W., Pozarlik, A.K., Shahi, M.   +5 more
core   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

THERMO-MECHANICAL COUPLING BETWEEN THE FLOW OF STEAM AND DEFORMATION OF THE VALVE DURING START-UP OF THE 200MW TURBINE

TASK Quarterly, 2001
The lifetime estimation of power station structures and components, subjected to fatigue loading, is essential for determining the moment of repair or replacement. Therefore the degradation behaviour and damage development within material should be very
MARCIN BIELECKI, MICHAŁ KARCZ, WOJCIECH RADULSKI, JANUSZ BADUR   +3 more
doaj  

Separation of the strain components for use in strainrange partitioning [PDF]

Two methods are presented for separating the inelastic strain components of a complex hysteresis loop so that strainrange partitioning formulas can be applied to accurately determine cyclic life at elevated temperatures.
Halford, G. R., Manson, S. S., Nachtigall, A. J.   +2 more
core   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

The strainrange partitioning behavior of an advanced gas turbine disk alloy, AF2-1DA [PDF]

The low-cycle, creep-fatigue characteristics of the advanced gas turbine disk alloy, AF2-1DA have been determined at 1400 F and are presented in terms of the method of strainrange partitioning (SRP).
Halford, G. R., Nachtigall, A. J.
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Life prediction modeling based on strainrange partitioning [PDF]

Strainrange partitioning (SRP) is an integrated low-cycle-fatigue life predicting system. It was created specifically for calculating cyclic crack initiation life under severe high-temperature fatigue conditions.
Halford, Gary R.
core   +1 more source