Results 31 to 40 of about 99,751 (297)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Creep behavior and cavitation evolution of 15CrMoG steel at high temperatures

open access: yesAdvances in Mechanical Engineering, 2019
15CrMoG steel is a type of heat-resistant steel frequently used in boiler and piping systems. Creep properties of the 15CrMoG steel at service temperatures are not much documented due to the difficulties in obtaining long-term creep data.
Jingping Pan   +3 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

On Creep and Relaxation

open access: yesJournal of Applied Physics, 1957
The creep function for the ``National Bureau of Standards'' polyisobutylene at 25°C is calculated from the relaxation function, using the integral equation connecting them. The calculated function is shown to be correct in its initial slope, to satisfy the inequality φ(t)ψ(t)⩽1 throughout, and to approach satisfactorily the independently determined ...
Hamming, Richard W., Hopkins, I.L.
openaire   +3 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Creep Model and Experimental Verification of Sandstone under the Coupled Effect of Chemical Corrosion and Temperature

open access: yesApplied Sciences
The Nishihara creep model is an extremely effective method in the field of sandstone creep model research. However, the Nishihara creep model curve for sandstone under the marine environment (the coupled effect of chemical corrosion and temperature) does
Xia Xiu   +5 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Creep Damage Evaluation using Uniaxial Miniature Specimens for Multiaxially Damaged Components [PDF]

open access: yesMATEC Web of Conferences, 2019
This study discusses a method of evaluating multiaxial creep damage for high temperature components subjected to multiaxial creep damage utilizing a miniature creep testing.
Kosaka Rui   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Study on Creep Characteristics and Constitutive Relation of Fractured Rock Mass

open access: yesShock and Vibration, 2020
In order to effectively describe the whole creep process of fractured rock mass, triaxial unloading creep tests were carried out on prefractured coal samples using constant axial pressure and graded unloading confining pressure, and the axial and lateral
Maotong Li   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy