YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Experimental Study on Creep of New Concrete Mixtures
The aim of this study was to experimentally investigate the creep behavior of developed concrete compositions in order to evaluate the possibility of using glass powder and small clay particles as active additives in concrete by replacing cement. Several
Sprince, Andīna +2 more
core +1 more source
Effect of Processing Parameters on the Creep Behavior and Integrity of Plasma-Sprayed Thermal Barrier Coatings on Ti-6Al-4V. [PDF]
Rodrigues BC +3 more
europepmc +1 more source
Influence of Post-Bond Heat Treatment on Microstructure and Creep Behavior of the Brazed Single-Crystal Nickel Superalloy. [PDF]
Hou X +5 more
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Creep behavior and microstructural evolution of sliding zone soil in slow-moving landslides in the Three-Gorges Reservoir area. [PDF]
Sun S +5 more
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Influence of defect shape on the creep behavior and damage evolution of coal rock using an improved model. [PDF]
Zhao T +5 more
europepmc +1 more source
A Mixed Iteration Method to Determine the Linear Material Parameters in the Study of Creep Behavior of the Composites. [PDF]
Katouzian M, Vlase S, Scutaru ML.
europepmc +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source

