Results 41 to 50 of about 29,556 (312)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Interpretation of Experimental Observation Data for the Development of Mechanisms based Creep Damage Constitutive Equations for High Chromium Steel

open access: yes, 2015
It is very important to design a safe factor or estimating the remain lifetime for electric power plant components of steam pipes which mostly manufacture by high chromium steels and work at high temperature and low stress level.
Yang, Xin   +5 more
core   +1 more source

Creep Rupture Behavior of Polyacetal

open access: yesKOBUNSHI RONBUNSHU, 2004
ポリアセタールの引張クリープ破壊特性を80℃で測定し, ホモポリマーとコポリマーを比較しそのメカニズムを考察した. クリープ破壊機構はクリープ荷重と破壊寿命の相関よりZhurkovの式を用いて活性化体積 (υc) を算出し, 以下のことが明らかになった. (1) ポリアセタールのυcは分子量とともに大きくなる. (2) ホモポリマーに比してコポリマーのυcは大きくコボリマーの方が破壊寿命の荷重依存性が大きいことに対応する. また, 破断面の電子顕微鏡観察からクリープの破壊起点は延性挙動であった. そのため, υcの値を引張変形挙動における引張速度と降伏強度の関係からEyringの式を使って算出した活性化体積 (υy) と比較した. 各材料のυcとυyは同じオーダーの値を示し, ほぼ, υc=1.6υ
TAJIMA, Yoshihisa, OHNUMA, Hiroshi
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Performance based creep life estimation for gas turbines application [PDF]

open access: yes, 2011
Accurate and reliable component life prediction is crucial to ensure both the safety and economics of gas turbine operations. In the pursuit of improved accuracy and reliability, current model-based creep life estimation methods have become more and ...
Abdul Ghafir, Mohammad Fahmi Bin
core  

Transitions in Creep Behavior

open access: yesMaterials Transactions, JIM, 1996
Under creep conditions at constant temperature, it is well known that transitions may occur between different flow mechanisms depending upon the level of the applied stress. For example, the transitions between the viscous glide of dislocations and control by dislocation climb are now well established in the creep of solid solution alloys.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Application of the linear matching method to creep-fatigue failure analysis of cruciform weldment manufactured of the austenitic steel AISI type 316N(L)

open access: yes, 2012
This paper demonstrates the recent extension of the Linear Matching Method (LMM) to include cyclic creep assessment [1] in application to a creep-fatigue analysis of a cruciform weldment made of the stainless steel AISI type 316N(L)
Chen, Haofeng, Gorash, Yevgen
core   +1 more source

Creep and creep crack growth behaviors for base, weld, and heat affected zone in a grade 91 weldment

open access: yesNuclear Engineering and Technology, 2021
This study investigated the creep and creep crack growth (CCG) behavior of the base metal (BM), weld metal (WM), and heat affected zone (HAZ) in a Gr. 91 weldment, which was made by a shield metal arc weld process.
Woo-Gon Kim   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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