Results 51 to 60 of about 146,033 (308)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Geofluids, 2021 The hazards induced by stratified rock mass creep are still one of the major problems that threaten the safety of underground engineering. This paper takes safe construction of underground roadway in Urumqi mining area as the research background. In this
Yiran Yang +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Experimental and modeling study of salt rock creep behavior under loading and unloading history
工程科学学报The influence of loading and unloading history on creep deformation suggests that the cyclic stress environment in underground engineering (e.g.: excavation, backfilling, and unloading) can significantly impact the long-term stability of salt rock.
Fan YANG +4 more
doaj +1 more source
Creep Evaluation of (Orthotic) Cast Materials During Simulated Clubfoot Correction [PDF]
, 2012 The Ponseti method is a widely accepted and highly successful conservative treatment of pediatric clubfoot that relies on weekly manipulations and cast applications.
Altiok, H. +4 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Creep model of roadway surrounding rock considering hardening effect and damage effect.
PLoS ONEThe influence of confining pressure on creep characteristics was analyzed by carrying out creep tests of rocks under different confining pressures. A new creep model of roadway surrounding rock considering the combined influence of hardening effect and ...
Hongmiao Lv
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Study on Creep Mechanical Properties of Non-Water Reacting Polyurethane Grouting Material
Advances in Materials Science and Engineering, 2022 Non-water reacting polyurethane is a new type of grouting material for support reinforcement and emergency rescue, whose creep mechanical behavior is directly related to the stability and safety of the reinforcement project.
Heng Liu +4 more
doaj +1 more source