Results 151 to 160 of about 21,077 (297)

Study on Creep Behavior and Constitutive Model of Carbonaceous Mudstone Under Hydro-mechanical Coupling

工程科学与技术
ObjectiveCarbonaceous mudstone exhibits low mechanical strength, water-induced disintegration, and reduced structural compactness. It is widely distributed in the mountainous strata of Southwestern China, where tunneling activities frequently traverse ...
YU Mingyuan, LIU Yaoru, HUANG Shuai, LIU Baoguo, WU Chao   +4 more
doaj  

Effect of Montmorillonite Nano Admixture on Long-term Deformations of Concrete

The purpose of the present research is to evaluate the possibility of using montmorillonite mineral nano particles (MNP) as active additives in concrete compositions in order to improve mechanical characteristics of concrete.
Sprince, Andīna, Korjakins, Aleksandrs, Pakrastiņš, Leonīds, Šahmenko, Genādijs   +3 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Experimental Study on Creep Characteristics of Microdefect Articular Cartilages in the Damaged Early Stage. [PDF]

J Healthc Eng, 2019
Gong H, Men Y, Yang X, Li X, Zhang C.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Creep Characteristics and Damage Constitutive Model of White Sandstone Under Short-Term Freeze-Thaw Cycles. [PDF]

Materials (Basel)
Zhang H, Li Y, Zeng P, Zhao K, Shen D, Yang X.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Uniaxial creep characteristics and constitutive model of arkose sandstone with different moisture contents under repeated freeze thaw cycles. [PDF]

Sci Rep
Chen T, Chen Y, Wu P, Cao X, Kong L, Chang Z.   +5 more
europepmc   +1 more source

Investigation into the switching characteristics of gold coated carbon nanotubes under low current conditions

, 2014
Gold coated multi-walled carbon nanotubes (Au/MWCNT) are a novel composite material, which have been investigated for use as an electrical contact surface.
Chianrabutra, Chamaporn
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source