Results 131 to 140 of about 21,077 (297)

Nanoindentation Study on the Creep Characteristics and Hardness of Ion-Irradiated Alloys. [PDF]

Materials (Basel), 2020
Zhu Z, Huang H, Liu J, Ye L, Zhu Z.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

[Research progress in creep characteristics of lumbar intervertebral disc]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2020
Wang C, Shi Z.
europepmc   +1 more source

Creep Deformations on High Strength Concrete Made of Montmorillonite Mineral Nano Particles

This paper introduces the recent state of research on creep of new concrete made by montmorillonite mineral nano particles (MNP) and then comparing them with control specimens made from reference concrete.
Sprince, Andīna, Korjakins, Aleksandrs, Pakrastiņš, Leonīds   +2 more
core  

Creep Characteristics and Model of Key Unit Rock in Slope Potential Slip Surface

, 2019
The creep characteristics of the key unit rock in a slope potential slip surface play an important role in the evolution of slope slip. In this research, a systematic restrictive shear creep experimental study was conducted to investigate the restrictive
Zhang, Huan, Zhang, Xiangyang, Li, Huahua, Wang, Yu, Wang, Tao, Zhao, Hongbao   +5 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Energy-based nonlinear damage creep model considering the influence of the concrete creep rate

Frontiers in Materials
In order to study the influence of confining pressure on the deformation of concrete, triaxial compression and creep tests under different confining pressures are carried out using a combination of laboratory tests and theoretical analysis.
Lu Wang
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Creep Characteristics of Drained Clays

Nihon Reoroji Gakkaishi(Journal of the Society of Rheology, Japan), 1974
YAMANOUCHI, Toyotoshi, YASUHARA, Kazuya
openaire   +2 more sources