Results 121 to 130 of about 4,982 (304)
Crack Growth Resistance Characteristics Determination Algorithm for Creep-fatigue Interaction
, 2016 A creep-fatigue crack growth rate interpretation method and algorithm and test results are described. The algorithm allows to obtain a crack growth rate diagram in terms of creep stress intensity factor.
Shlyannikov, V.N. +2 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
Creep-fatigue behavior analysis of the 310 NBN steel: Experimental and life prediction
Journal of Materials Research and TechnologyWith the increasing challenge of extending the service life of structural steels components subjected to high-temperature environments, there is an urgent need to investigate the mechanisms of creep-fatigue and to develop new steels that can effectively ...
Julianna Magalhaes Garcia +4 more
doaj +1 more source
A theoretical and computational framework for studying creep crack growth. [PDF]
Int J Fract, 2017 Elmukashfi E, Cocks ACF.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source
Creep damage is a time-dependent deformation in metals under a constant stress at high temperature condition. Since the 1980s, high chromium alloy steel P91 (9%Cr-1%Mo-0.25%V) is highly demanded in high temperature industries (Saha, 2003).
An, Lili
core
Finite Element Damage Analyses for Predictions of Creep Crack Growth
, 2010 This paper provides the virtual simulation method for creep crack growth test, based on finite element (FE) analyses with damage mechanics. Creep tests of smooth bars are used to quantify the constants of creep constitutive equation.
Chang-Sik Oh +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study explored how effective nickel aluminide coatings are obtained in providing oxidation resistance applied to the Inconel 738 alloy, modeling with diffusion models. In the present study, kinetics and thermal behavior of the Inconel 738 alloy were studied by the low‐temperature thermoreactive aluminizing process, which was carried out at 625°C ...
Gozde Celebi Efe +4 more
wiley +1 more source