Results 111 to 120 of about 42,527 (308)

Life Prediction of Crack Growth for P92 Steel Under Strain-Controlled Creep–Fatigue Conditions Using a Sharp Notched Round Bar Specimen

Metals
Testing and the estimation methods for predicting the life of crack initiation and crack growth for P92 steel using a circular sharp notched round bar specimen (CNS) under strain-controlled creep and fatigue conditions have been reported previously.
A. Toshimitsu Yokobori, Go Ozeki, Kazutaka Jinno, Hiroaki Seino, Ryuji Sugiura, Isamu Nonaka   +5 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Crystallographic crack propagation rate in single-crystal nickelbase superalloys

MATEC Web of Conferences, 2018
Single-crystal nickel-base superalloys are often used in the hot sections of gas turbines due to their good mechanical properties at high temperatures such as enhanced creep resistance.
Busse Christian, Palmert Frans, Wawrzynek Paul, Sjödin Björn, Gustafsson David, Leidermark Daniel   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Optical method for measuring slow crack growth in cementitious materials [PDF]

, 2018
The double-torsion (DT) test is commonly used to calculate slow or subcritical crack velocities in (quasi-)brittle engineering materials directly from the measured load relaxation of notched DT-specimens.
Bisschop, J., Cai, W.
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Scalar, vectorial and tensorial damage parameters from the mesoscopic background

, 2007
In the mesoscopic theory a distribution of different crack sizes and crack orientations is introduced. A scalar damage parameter, a second order damage tensor and a vectorial damage parameter are defined in terms of this distribution function.
Papenfuss, C., Ván, P.
core   +2 more sources

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

Creep-fatigue behavior analysis of the 310 NBN steel: Experimental and life prediction

Journal of Materials Research and Technology
With the increasing challenge of extending the service life of structural steels components subjected to high-temperature environments, there is an urgent need to investigate the mechanisms of creep-fatigue and to develop new steels that can effectively ...
Julianna Magalhaes Garcia, Gabriel P. Potirniche, Robert Stephens, Sergio Neves Monteiro, Luiz Paulo Brandao   +4 more
doaj   +1 more source