Results 111 to 120 of about 17,423 (316)
Microstructural and property assessment of creep aged 12cr steel after welding
, 2013 Includes bibliographical references.The electricity public utility of Eskom (South Africa) has an ageing fleet of power generation equipment and due to shortage of capacity there is limited time for maintenance and replacements.
Molokwane, Teboho Jacob
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The Development and Validation of the Creep Damage Constitutive Equations for P91 Alloy
This paper presents research on the validation of a set of creep damage constitutive equations for P91 alloy under multi-axial states of stress, and its applicability under lower stress level.
Yang, Xin, Xu, Qiang, Lu, Zhongyu
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Creep in fibre-reinforced polymer mat composites
, 2007 Tensile creeps have been conducted upon a woven, glass-fibre laminated epoxy composite and a 0/90° cross ply, carbon fibre reinforced epoxy composite. For the laminate loading was aligned with a fibre direction.
Dix, S, Garner, AF, Rees, DWA
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Modeling creep damage of an aluminum–silicon eutectic alloy
, 2013 Aluminum–silicon casting alloys are widely used in the automotive industry. The aim of this article is to analyze creep and creep damage of the eutectic AlSi12CuNiMg cast piston alloy and to present a constitutive model that reflect basic features of ...
Altenbach, Holm +2 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2013 Diffusion dominates the creep deformation at low stress range for high chromium steel P91. Brittle creep fracture is caused by cavity nucleation, growth and coalescence of cavities and large precipitates (Laves phase and M23C6) at grain boundary under ...
Xu, Qiang +3 more
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Creep damage model for deep salt rock under temperature and stress coupling effect
Meitan xuebaoAs the demand on the construction salt rock storage increases in China, the shallow suitable deposits have been gradually exhausted, as such, the utilization shift from shallow to deep salt deposits is an inevitable trend.
Shengli ZHANG +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Theoretical backgrounds of durability analysis by normalized equivalent stress functionals
, 2003 Generalized durability diagrams and their properties are considered for a material under a multiaxial loading given by an arbitrary function of time. Material strength and durability under such loading are described in terms of durability, safety factor ...
Mikhailov, SE
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