Results 51 to 60 of about 17,423 (316)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A novel nonlinear creep model based on damage characteristics of mudstone strength parameters.
PLoS ONE, 2021 Mudstone interlayer is a weak layer in rock engineering. When it is subjected to continuous stress higher than its damage threshold, due to the dislocation of particles in mudstone crystals and the expansion of cracks, mudstone strength is gradually ...
Bin Hu +4 more
doaj +1 more source
The tertiary creep and necking of creep damaging solids
Acta Metallurgica, 1986 Abstract Tertiary creep and necking of bars composed of creep damaging material are investigated subject to the condition of constant applied load. The creep-damage constitutive model employed in the study is based on the concept of constrained cavity growth which characterizes the phenomenon of grain boundary cavitation in polycrystalline metals ...
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Techniques in Developing Finite Element Software for Creep Damage Analysis
, 2013 There is a need for a computational tool for analyzing creep damage problems for the research community and high temperature industries, and dedicated in-house software still has its merits and advantages.
Tan, Feng +12 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Microstructural modelling of creep crack growth from a blunted crack [PDF]
, 1998 The effect of crack tip blunting on the initial stages of creep crack growth is investigated by means of a planar microstructural model in which grains are represented discretely. The actual linking-up process of discrete microcracks with the macroscopic
Giessen, E. van der +4 more
core
Nonlinear Creep Constitutive Model of Rock Considering Hardening Effect
GeofluidsThe creep of rock is a complex mechanical phenomenon driven by internal stress adjustment and the interplay between hardening and damage effects. To precisely capture the nonlinearity of rock creep and the law of accelerated deformation, a hardening ...
Dipeng Zhu +9 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source