Results 81 to 90 of about 17,423 (316)
Creep crack growth assessment in terms of continuum damage mechanics
MATEC Web of Conferences, 2018 The stress, strain rate, and process zone with respect to the creep-crack growth in compacttension C(T) specimen is analyzed by employing damage-evolution equations.
Shlyannikov Valery, Tumanov Andrey
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A parametric study on creep-fatigue strength of welded joints using the linear matching method
, 2013 This paper presents a parametric study on creep-fatigue strength of the steel AISI type 316N(L) weldments of types 1 and 2 according to R5 Vol. 2/3 Procedure classification at 550◦C.
Chen, Haofeng, Gorash, Yevgen
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Competition between mesoplasticity and damage under HCF – Elasticity/damage shakedown concept [PDF]
, 2007 Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112306003240The aim of this paper is to present new modelling dedicated to multiaxial high cycle fatigue (HCF), and applied to polycrystalline metals.
DRAGON, André +2 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Experimental characterization and numerical modeling of micromechanical damage under different stress states [PDF]
, 2013 The use of HSLA steels for the manufacture of automotive components is interesting from an engineering point of view. This family of steels, while possessing high strength, also has good formability and can be used in forming manufacturing processes.
GERMAIN, Guénaël +3 more
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Influence of Creep Damage on the Fatigue Life of P91 Steel. [PDF]
Materials (Basel), 2022 Mroziński S, Lis Z, Egner H.
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
An evaluation of operation and creep life of stationary gas turbine engine [PDF]
, 2012 During operation, gas turbine components undergo various types of timedependent degradation due to high temperatures and mechanical loading. In the case of stationary GT engines for mechanical power, creep failure mechanism problems are a very common ...
Eshati, Samir
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