Results 231 to 240 of about 8,285 (310)

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

In-Vitro Evaluations of Shape Memory Polymer Scaffolds With Tunable Architecture for the Endovascular Embolization of Unruptured Intracranial Aneurysms. [PDF]

J Biomech Eng
Cabaniss TL, Colby G, Liu Y, Lee H, Bohnstedt BN, Lee CH.   +5 more
europepmc   +1 more source

Creep Rupture of Fibers

Sen-ito Kogyo, 1970
openaire   +2 more sources

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Molecular Creep Induced Fatigue Rupture of Fibrin Clots. [PDF]

Adv Sci (Weinh)
Liu D, Jia Z, Liu B, Hou J, Bao R, Wang M.   +5 more
europepmc   +1 more source

CREEP DEFORMATION AND CREEP RUPTURE OF FIBRE REINFORCED COMPOSITES

, 1980
openaire   +2 more sources

The Development of Finite Element Analysis Software for Creep Damage Analysis

, 2013
Tan, Feng, Xu, Qiang, Xu, Donglai, Liu, Dezheng, Lu, Zhongyu, Xu, Dong Lai   +5 more
core  

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source

Unveiling the rheological secrets of hydrogels: from lab to clinical translation. [PDF]

RSC Adv
Shan J, Jiao W.
europepmc   +1 more source

Emergent Tissue Stability from Intercellular Bond Dynamics during Cyclic Mechanical Loading

Papafilippou E, Bonfanti A, Charras G, Kabla A.   +3 more
europepmc   +1 more source