Results 141 to 150 of about 29,880 (311)

Research of Method for Solving Relaxation Modulus Based on Three-Point Bending Creep Test. [PDF]

Materials (Basel), 2019
Sun Y, Gu Z, Wang J, Yuan X.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Experimental Creep Tests on Concrete Made with Montmorillonite Nano Particles

The purpose of this research is to investigate and characterize the time-dependent behavior of new concrete compositions made by replacing cement with secondary aggregates — small clay particles — and then comparing them with control specimens made from ...
Sprince, Andīna, Korjakins, Aleksandrs, Pakrastiņš, Leonīds   +2 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Creep Deformations on High Strength Concrete Made of Montmorillonite Mineral Nano Particles

This paper introduces the recent state of research on creep of new concrete made by montmorillonite mineral nano particles (MNP) and then comparing them with control specimens made from reference concrete.
Sprince, Andīna, Korjakins, Aleksandrs, Pakrastiņš, Leonīds   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Evaluation of Asphalt Mixture Low-Temperature Performance in Bending Beam Creep Test. [PDF]

Materials (Basel), 2018
Pszczola M, Jaczewski M, Rys D, Jaskula P, Szydlowski C.   +4 more
europepmc   +1 more source

On the Methed of Creep Test of Metals

Journal of the Society of Mechanical Engineers, 1943
OKUDA, Katumi, UNO, Tukumo
openaire   +3 more sources

Creep Testing of Platinum Alloys

Platinum Metals Review, 1957
An account is given of the Johnson Matthey creep-testing laboratory for determining life-to-rupture under constant stress at temperatures from 400° to 900°C, using miniature creep-testing ...
openaire   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source