Results 141 to 150 of about 177,805 (313)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Research of Method for Solving Relaxation Modulus Based on Three-Point Bending Creep Test. [PDF]
Materials (Basel), 2019 Sun Y, Gu Z, Wang J, Yuan X.
europepmc +1 more source
Computer programs to characterize alloys and predict cyclic life using the total strain version of strainrange partitioning: Tutorial and users manual, version 1.0 [PDF]
This manual presents computer programs for characterizing and predicting fatigue and creep-fatigue resistance of metallic materials in the high-temperature, long-life regime for isothermal and nonisothermal fatigue.
Saltsman, James F.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Evaluation of Asphalt Mixture Low-Temperature Performance in Bending Beam Creep Test. [PDF]
Materials (Basel), 2018 Pszczola M +4 more
europepmc +1 more source
Stress redistribution due to creep in nimonic 90 ministry of aviation contract no. PD/28/021 report for the period June, 1965 to July, 1966: part 2 [PDF]
, 1966 Part I of this report, dated September 1965, deals mainly with the design and construction of the special apparatus to simulate the stress redistribution occurring during the creep of a cooled turbine blade.
Clifton, T. E.
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Damage mechanisms in bithermal and thermomechanical fatigue of Haynes 188 [PDF]
Post failure fractographic and metallographic studies were conducted on Haynes 188 specimens fatigued under bithermal and thermomechanical loading conditions between 316 and 760 C.
Halford, Gary R., Kalluri, Sreeramesh
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source