Results 41 to 50 of about 29,880 (311)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Interpretation of Experimental Observation Data for the Development of Mechanisms based Creep Damage Constitutive Equations for High Chromium Steel

open access: yes, 2015
It is very important to design a safe factor or estimating the remain lifetime for electric power plant components of steam pipes which mostly manufacture by high chromium steels and work at high temperature and low stress level.
Yang, Xin   +5 more
core   +1 more source

Temperature-dependent creep aging behavior of 2A14 aluminum alloy

open access: yesJournal of Materials Research and Technology, 2022
The creep deformation behavior, aging hardening response and microstructure evolution of 2A14 aluminum alloy (Al-4.81wt%Cu-0.66wt%Mg-0.97wt%Si) at different temperatures have been systematically investigated by creep test, tensile test, transmission ...
Wenfang Yu   +9 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Creep Characteristics of Reconstituted Silty Clay under Different Pre-Loading Path Histories

open access: yesBuildings
Due to the long-term deformation settlement of foundations, issues such as damage and functional failure of buildings and structures have long been a concern in the engineering field.
Bin Xiao, Peijiao Zhou, Shuchong Wu
doaj   +1 more source

High Temperature Random Stack Creep Property of NI-CR-AL based Powder Porous Metal Manufactured with Powder Sintering Process [PDF]

open access: yesArchives of Metallurgy and Materials, 2019
Recently, attempts have been made to use porous metal as catalysts in a reactor for the hydrogen manufacturing process using steam methane reforming (SMR).
Tae-Hoon Kang   +3 more
doaj   +1 more source

Experimental study on creep behaviors of red sandstone in Sichuan and Chongqing under acid corrosion

open access: yes地质科技通报, 2022
The creep characteristics of rock have an important effect on the long-term stability of rock engineering. Especially under the action of acid rain and other water chemistry, the rock microstructure is destroyed, and the creep characteristics and ...
Ni Xie, Dinghao Wang, Yang Lü, Qing Gao
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Development and application of a new multistage confined dynamic creep test for asphalt [PDF]

open access: yes, 2018
Research on well-designed heavy-traffic flexible pavements in areas with elevated temperatures has shown that their service life is a function of the creep performance of their top asphalt layers.
Zargar, Majid
core  

Experimental study of creep properties of silty mudstone under triaxial compression

open access: yes工程科学与技术, 2012
:In order to reveal the creep properties of silty mudstone in Badong Formation strata in the Three Gorges area, the creep test of saturated silty mudstone under triaxial compression was carried out on the RLJW-2000 rock microcomputer-controlled rheology ...
Li ya-li
doaj  

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