Creosote bush lignans for human disease treatment and prevention: Perspectives on combination therapy [PDF]
Journal of Traditional and Complementary Medicine, 2015 The medicinal properties of the most successful plant in the deserts of the western hemisphere, the creosote bush (Larrea tridentata), are evidenced by the long traditional usage of the plants by the Native Americans Indian tribes in Southwestern North ...
John Gnabre, Robert Bates, Ru Chih Huang
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Creosote Bush (Larrea tridentata) Extract Assessment as a Green Antioxidant for Biodiesel [PDF]
Molecules, 2019 In this work, the antioxidant properties of methanolic extract of Larrea tridentata were assessed through the free radical scavenging method, ferric reducing antioxidant power and oxygen radical absorbance capacity.
Carlos A. Sagaste +8 more
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Rodents consuming the same toxic diet harbor a unique functional core microbiome [PDF]
Animal MicrobiomeGut microbiota are intrinsic to an herbivorous lifestyle, but very little is known about how plant secondary compounds (PSCs), which are often toxic, influence these symbiotic partners.
Tess E. Stapleton +3 more
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Dietary-Driven Gene Expansion. [PDF]
Clin Pharmacol TherGene duplication has been shown to drive molecular evolution, with dietary pressures expanding detoxification genes across species. In humans, CYP2D6 gene duplications enhance alkaloid and drug metabolism, reflecting ancient dietary adaptations. Similarly, tobacco‐feeding aphids amplify CYP6CY3 for nicotine and insecticide resistance, and as recently ...
Ingelman-Sundberg M.
europepmc +2 more sources
Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. [PDF]
PLoS ONE, 2015 Nordihydroguaiaretic acid (NDGA), the main metabolite of Creosote bush, has been shown to have profound effects on the core components of the metabolic syndrome (MetS), lowering blood glucose, free fatty acids (FFA) and triglyceride (TG) levels in ...
Haiyan Zhang +11 more
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In Vitro Antiviral Activity of Nordihydroguaiaretic Acid against SARS-CoV-2 [PDF]
Viruses, 2023 The coronavirus infectious disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been spreading rapidly worldwide, creating a pandemic.
Erendira Villalobos-Sánchez +6 more
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The desert woodrat (Neotoma lepida) induces a diversity of biotransformation genes in response to creosote bush resin [PDF]
Comparative Biochemistry and Physiology Part - C: Toxicology and PharmacologyLiver biotransformation enzymes have long been thought to enable animals to feed on diets rich in xenobiotic compounds. However, despite decades of pharmacological research in humans and rodents, little is known about hepatic gene expression in specialized mammalian herbivores feeding on toxic diets.
Teri Orr +2 more
exaly +4 more sources
Insights Into Spatial Orientation and Cognition in Tarantulas (Araneae: Theraphosidae) Under Natural Conditions, With Notes on Possible Ontogenetic Niche Shifts. [PDF]
Ecol EvolCognitive studies on spiders have largely ignored mygalomorphs, such as tarantulas, and almost completely lack field‐based observations. We present nine observations of arboreal and fossorial New World tarantulas, including a blind cave‐dwelling species, providing evidence for possible experience‐based navigation and spatial learning during foraging ...
Zamani A, West RC.
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Creosote growth rate and reproduction increase in postfire environments [PDF]
Ecology and Evolution, 2019 Human activities are changing patterns of ecological disturbance globally. In North American deserts, wildfire is increasing in size and frequency due to fuel characteristics of invasive annual grasses.
Rebecca Lee Molinari +5 more
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Polyploidy in creosote bush (Larrea tridentata) shapes the biogeography of specialist herbivores. [PDF]
J Biogeogr, 2019 AbstractAimWhole‐genome duplication (polyploidy) can influence the biogeography and ecology of plants that differ in ploidy level (cytotype). Here, we address how two consequences of plant polyploidy (parapatry of cytotypes and altered species interactions) shape the biogeography of herbivorous insects.LocationWarm deserts of North America.TaxaGall ...
O'Connor TK, Laport RG, Whiteman NK.
europepmc +6 more sources