Results 1 to 10 of about 9,990 (160)

Antimicrobial Activity and Molecular Mechanism of the CRES Protein [PDF]

PLoS ONE, 2012
Cystatin-related epididymal spermatogenic (CRES) protein, a member of the cystatin superfamily of cysteine protease inhibitors (also known as CST8), exhibits highly specific, age-dependent expression in mouse testis and epididymis.
Li Wang, Qing Yuan, Sunhong Chen, Heng Cai, Meige Lu, Yue Liu, Chen Xu   +6 more
exaly   +2 more sources

The landscape of regulatory element evolution in a C4 perennial grass [PDF]

BMC Genomics
Background Gene regulatory evolution is a well-known source of phenotypic diversity and adaptive evolution. Although cis-regulatory elements (CREs) play a vital role in gene expression evolution, the molecular evolution of CREs remains mostly unknown due
Taslima Haque, Govinal Badiger Bhaskara, Robert J. Schmitz, Thomas E. Juenger   +3 more
doaj   +2 more sources

Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex [PDF]

Nature Communications
Single-cell spatial transcriptomes have demonstrated molecular and cellular diversity in the brain, but gene regulatory mechanisms underlying transcriptomic profiles and disease pathogenesis remain largely unknown in primates.
Juan Meng, Cheng Chen, Zhiyong Zhu, Yongkang Sun, Yiming Huang, Kaijie Hu, Jiqiang Fu, Luyan Wu, Ling Li, Yiqin Bai, Tianyi Fei, Zhen Liu, Chao Li, Zhiming Shen, Longqi Liu, Chengyu Li, Tao Song, Cirong Liu, Muming Poo, Shiping Liu, Ying Lei, Yidi Sun   +21 more
doaj   +2 more sources

High-resolution map of chromatin accessibility - insights into the focused binding of a large number of transcription factors [PDF]

Epigenetics & Chromatin
Background Emerging evidence has shown the common occupancy of dozens to hundreds of transcription factors (TFs) on cis-regulatory elements (CREs), yet the underlying details are largely unknown. Results In this study, leveraging extensive collections of
Iris Zhu, David Landsman
doaj   +2 more sources

Protocol to study sufficiency of cis-regulatory elements in mouse embryonic stem cells using a CRISPR-mediated knockin approach

STAR Protocols, 2022
Summary: cis-regulatory elements (CREs) orchestrate the spatiotemporal control of gene expression. The regulatory activity of CREs is typically assessed by reporter assays, in which CREs are studied outside their endogenous context.
Tomas Pachano, Alvaro Rada-Iglesias
doaj   +1 more source

Elucidation of Novel cis-Regulatory Elements and Promoter Structures Involved in Iron Excess Response Mechanisms in Rice Using a Bioinformatics Approach

Frontiers in Plant Science, 2021
Iron (Fe) excess is a major constraint on crop production in flooded acidic soils, particularly in rice cultivation. Under Fe excess, plants activate a complex mechanism and network regulating Fe exclusion by roots and isolation in various tissues.
Yusuke Kakei, Hiroshi Masuda, Naoko K. Nishizawa, Hiroyuki Hattori, May Sann Aung, May Sann Aung   +5 more
doaj   +1 more source

Examining the Development of a Geothermal Risk Mitigation Scheme in Greece

Clean Technologies, 2022
Geothermal project development entails a number of risks, the most significant of which is the geological risk. The introduction of a risk mitigation scheme (RMS) might enable project developers to shift some of the geological risk to public or private ...
Spyridon Karytsas, Dimitrios Mendrinos, Theoni I. Oikonomou, Ioannis Choropanitis, Attila Kujbus, Constantine Karytsas   +5 more
doaj   +1 more source

Stella‐Cre mice are highly efficient Cre deleters [PDF]

genesis, 2011
AbstractCre‐loxP recombination is widely used for genetic manipulation of the mouse genome. Here, we report generation and characterization of a new Cre line, Stella‐Cre, where Cre expression cassette was targeted to the 3′ UTR of the Stella locus. Stella is specifically expressed in preimplantation embryos and in the germline.
Liu, Pentao, Liu, Hui, Wang, Wei, Chew, Su Kit, Lee, Song Choon, Li, Juan, Vassiliou, George S., Green, Tony, Futreal, P. Andrew, Bradley, Allan, Zhang, Shujun   +10 more
openaire   +4 more sources

Microwave Drying Kinetics of Chromium-Rich Electroplating Sludge

Metals, 2022
Chromium-rich electroplating sludge (CRES) is a hazardous solid waste with a high content of moisture requiring efficient drying before subsequent treatment. In this study, the microwave drying kinetics of CRES were examined. The results showed that CRES
Jian Zhang, Zhiwei Peng, Guanwen Luo, Ran Tian, Mingjun Rao   +4 more
doaj   +1 more source

Computational exploration of cis-regulatory modules in rhythmic expression data using the "Exploration of Distinctive CREs and CRMs" (EDCC) and "CRM Network Generator" (CNG) programs. [PDF]

PLoS ONE, 2018
Understanding the effect of cis-regulatory elements (CRE) and clusters of CREs, which are called cis-regulatory modules (CRM), in eukaryotic gene expression is a challenge of computational biology.
Pavlos Stephanos Bekiaris, Tobias Tekath, Dorothee Staiger, Selahattin Danisman   +3 more
doaj   +1 more source