Results 71 to 80 of about 11,846 (230)
Frontiers in Medicine, 2022 Glucocorticoids are commonly used to treat anti-GBM crescentic glomerulonephritis, however, the mechanism underlying its therapeutic effectiveness is not completely understood.
Xiaomei Wu +8 more
doaj +1 more source
Alterations of podocytes in a murine model of crescentic glomerulonephritis [PDF]
, 2018 Recent observations suggest a central role of podocytes in crescent formation. In experimental glomerulonephritis podocytes disrupt the parietal epithelial layer and attach on its basement membrane, thus forming bridges between the tuft and Bowman's ...
Besse-Eschmann, Valérie +3 more
core
Clinical &Translational Immunology, Volume 15, Issue 3, 2026.In IgA nephropathy (IgAN), innate and adaptive immune cells display distinct spatial compartmentalisation, with macrophages predominating within glomeruli and CD4+ T cells constituting the major immune population in inflammatory foci. Glomeruli with distinct pathological morphologies exhibit morphology‐dependent immune infiltration patterns and ...
Xing Chen +8 more
wiley +1 more source
Rare Bacteria Infecting the Heart and Affecting the Kidney of a Young Child
Case Reports in Nephrology and Dialysis, 2017 Rare bacteria can lead to infective endocarditis, which may lead to renal involvement as severe glomerulonephritis. We report our experience of a 12-year-old child who presented with infective endocarditis and blood culture-grown Gemella morbillorum – a ...
Gurinder Kumar +2 more
doaj +1 more source
Acta Physiologica, Volume 242, Issue 3, March 2026.ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica +3 more
wiley +1 more source
Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
, 2005 Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Anders, Hans-Joachim, Ninichuk, Volha
core +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley +1 more source
Immune complex type crescentic glomerulonephritis and ANCA-positivity in a nine-year-old girl
The Turkish Journal of Pediatrics, 2002 We report a nine-year-old girl who presented with the clinical and laboratory findings of rapidly progressive glomerulonephritis. She was found to be positive for both pANCA and cANCA.
Alper Soylu +4 more
doaj
Churg-Strauss Syndrome with Necrosis of Toe Tips [PDF]
, 2011 Churg-Strauss syndrome (CSS) is a granulomatous necrotizing vasculitis of unknown etiology associated with bronchial asthma. Despite affecting small to medium-sized vessels, necrosis of the digits due to vasculitis is extremely rare.
Hasegawa, Kenjiro +9 more
core +1 more source
Risk Factors of Disease Progression in IgA Nephropathy: A Systematic Review and Meta‐Analysis
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.ABSTRACT Objective IgA nephropathy (IgAN) is an important cause of chronic renal failure, and nearly all patients with IgAN are at risk of developing to end‐stage renal disease (ESRD) during their lifetime. This meta‐analysis aimed to identify and evaluate risk factors associated with the progression of IgAN patients.
Dan Xu +4 more
wiley +1 more source