Results 31 to 40 of about 66,502 (133)

Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus

mBio, 2021
Circular Rep-encoding single-stranded DNA (CRESS-DNA) viruses infect members from all three domains of life (Archaea, Prokarya, and Eukarya). The replicase (Rep) from these viruses is responsible for initiating rolling circle replication (RCR) of their ...
Elvira Tarasova, Sonali Dhindwal, Matthew Popp, Sakeenah Hussain, Reza Khayat   +4 more
doaj   +1 more source

In silico analysis of capsid and rep proteins in CRESS DNA viruses

, 2023
Abstract The circular rep-encoding single-stranded DNA viruses (CRESS DNA viruses) are among the smallest, with 2–6 kb ssDNA genomes that encode for a coat protein (C) and a replication protein (R). To comprehend the complexity and divergence of the C and R proteins, we have created predictive structural models of representative viruses ...
K. Selvaraj, Yagavi Yadhav, R. Selvarajan, Sangita Venkataraman   +3 more
openaire   +1 more source

EasyCen: A Lightweight Framework for Centromere Localisation and Repeat-Organisation Profiling in Telomere-to-Telomere Genomes. [PDF]

Mol Ecol Resour
ABSTRACT Accurate identification of centromeres in telomere‐to‐telomere (T2T) genomes remains difficult due to the rapid evolution of centromeric repeats and their lack of conserved sequence features. In this study, we present EasyCen, a lightweight sequence‐based framework for centromere identification and repeat‐architecture profiling across various ...
Lv Y, Li Y, Li J, Mu X.
europepmc   +2 more sources

DNA virome of ticks in the Northeast and Hubei provinces of China reveals diverse single-stranded circular DNA viruses

Parasites & Vectors, 2023
Background Ticks are medically important vectors capable of transmitting a variety of pathogens to and between host species. Although the spectrum of tick-borne RNA viruses has been frequently investigated, the diversity of tick-borne DNA viruses remains
Yuhang Liu, Lei Guo, Guoshuai Wang, Fei Gao, Zhongzhong Tu, Deming Xu, Lanshun Sun, Le Yi, Guoqiang Zhu, Changchun Tu, Biao He   +10 more
doaj   +1 more source

A New Circular Single-Stranded DNA Virus Related with Howler Monkey Associated Porprismacovirus 1 Detected in Children with Acute Gastroenteritis

Viruses, 2022
Putative replication-associated protein (REP) and capsid-like (CAP) proteins are encoded by circular single-stranded DNA viruses (CRESS DNA), which have been found in samples from most eukaryotic groups. However, the details of these viruses’ life cycles
Fabiola Villanova, Flávio Augusto de Padua Milagres, Rafael Brustulin, Emerson Luiz Lima Araújo, Ramendra Pati Pandey, V. Samuel Raj, Xutao Deng, Eric Delwart, Adriana Luchs, Antonio Charlys da Costa, Élcio Leal   +10 more
doaj   +1 more source

Pervasive Chimerism in the Replication-Associated Proteins of Uncultured Single-Stranded DNA Viruses

Viruses, 2018
Numerous metagenomic studies have uncovered a remarkable diversity of circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses, the majority of which are uncultured and unclassified. Unlike capsid proteins, the Reps show
Darius Kazlauskas, Arvind Varsani, Mart Krupovic   +2 more
doaj   +1 more source

Novel circular single-stranded DNA viruses identified in marine invertebrates reveal high sequence diversity and consistent predicted intrinsic disorder patterns within putative structural proteins

Frontiers in Microbiology, 2015
Viral metagenomics has recently revealed the ubiquitous and diverse nature of single-stranded DNA (ssDNA) viruses that encode a conserved replication initiator protein (Rep) in the marine environment.
Karyna eRosario, Ryan O. Schenck, Rachel C. Harbeitner, Stephanie N. Lawler, Mya eBreitbart   +4 more
doaj   +1 more source

New Type of Papillomavirus and Novel Circular Single Stranded DNA Virus Discovered in Urban Rattus norvegicus Using Circular DNA Enrichment and Metagenomics. [PDF]

PLoS ONE, 2015
Rattus norvegicus (R. norvegicus) are ubiquitous and their presence has several effects on the human populations in our urban areas on a global scale.
Thomas Arn Hansen, Helena Fridholm, Tobias Guldberg Frøslev, Kristín Rós Kjartansdóttir, Eske Willerslev, Lars Peter Nielsen, Anders Johannes Hansen   +6 more
doaj   +1 more source

Toxicological, histological and biochemical effects of Lepidium sativum seeds extract on Galleria mellonella L. (Lepidoptera: Pyralidae) larvae [PDF]

Catrina: The International Journal of Environmental Sciences, 2021
The greater wax moth Galleria mellonella L. is a serious destructive pest of honeybee colonies in the beekeeping industry all over the world. The larvae feed on almost all of the honeybee products and have the ability to completely destroy the bee colony,
Rehab El-Gendy
doaj   +1 more source

Viral metagenomic analysis of fecal samples from <i>Bos grunniens</i> on the Qinghai-Tibet Plateau reveals novel picornaviruses and diverse CRESS-DNA viruses. [PDF]

Front Cell Infect Microbiol
Introduction The Qinghai–Tibet Plateau (QTP), one of the most extreme environments on Earth, provides a unique natural setting for exploring viral diversity and evolution under conditions of high altitude, hypoxia, and intense ultraviolet radiation.
Chen J, Gong G, Su X, Song X, Zhang J, Wu P, Wang H, Shan T, Zhang W.   +8 more
europepmc   +4 more sources