Results 171 to 180 of about 2,561,602 (268)

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares, Jacy Bezerra Parmera, Pedro Augusto Sampaio Rocha‐Filho   +2 more
wiley   +1 more source

The Role of Musculoskeletal Ultrasound in Detecting Superior Cluneal Nerve Entrapment: Biomechanical Insights in Chronic Low Back Pain-A Pilot Study. [PDF]

Diagnostics (Basel)
Iudicelli G, Agostini F, Altarocca A, Ioppolo F, Narciso M, Conti M, Fisicaro A, Savina A, Nunno VD, Mangone M, Galletti S, Paoloni M.   +11 more
europepmc   +1 more source

In Vivo Mapping of Catecholaminergic Loss and Iron Deposition in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background The pathophysiology of Huntington's disease (HD) remains obscure. Magnetic resonance imaging (MRI) can reveal in vivo molecular changes related to disease pathology. Objectives To investigate catecholaminergic neuronal integrity and subcortical brain iron accumulation in HD employing neuromelanin‐sensitive MRI, and quantitative ...
Edoardo R. de Natale, Heather Wilson, Efstratios Karavasilis, Athanasia Liozidou, Chrisoula Kartanou, Georgios Velonakis, Jens Kuhle, Ioannis Zalonis, Georgia Karadima, Leonidas Stefanis, Georgios Koutsis, Marios Politis   +11 more
wiley   +1 more source

Differential Diagnosis of Posterior Buttock Pain: A Conceptual Review Based on Topographic Localization of Pain, Is It Really the Sacroiliac Joint? [PDF]

Int J Spine Surg
Reckling WC, Polly DW.
europepmc   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

Cytometry-based blood immune cell markers associated with clinical outcomes in systemic sclerosis: protocol for a systematic review. [PDF]

BMJ Open
Souffez M, Dumontet E, Lecureur V, Lescoat A, Ferrant J.   +4 more
europepmc   +1 more source

Sclerodactyly, CREST syndrome, proximal scleroderma. [PDF]

Annals of the Rheumatic Diseases, 1986
openaire   +2 more sources

Automated Segmentation of Median Nerve Cross‐Sectional Area in Healthy Controls and Patients With Carpal Tunnel Syndrome Using a Convolutional Neural Network

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims The cross‐sectional area (CSA) of the median nerve (MN) is a key parameter for confirming carpal tunnel syndrome (CTS) with ultrasound. This study evaluates the performance of a convolutional neural network (CNN) with a 2D U‐Net architecture for automated MN CSA segmentation in both healthy individuals and patients with CTS ...
Tom B. G. Olde Dubbelink, Erik Willemen, Bas Schippers, Jan Meulstee, Frouke A. P. Nijhuis, Ronald H. M. A. Bartels, Wim I. M. Verhagen   +6 more
wiley   +1 more source

Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [PDF]

Med Sci (Basel)
Erokhina MA, Vorotelyak EA, Vasiliev AV, Abdyev VK.   +3 more
europepmc   +1 more source