Results 1 to 10 of about 35,863 (248)

Creutzfeldt-Jakob disease. [PDF]

open access: bronzeBMJ, 1978
Summary The laboratory transmission to animals of an apparently degenerative disease of the nervous system, Creutzfeldt-Jakob disease (CJD), is now well established. Important questions arising from this observation are the possibility of natural transmission or infectivity and the existence of other similarly transmissible diseases ...
W.B. Matthews
openaire   +6 more sources

Creutzfeldt-Jakob disease

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2013
Creutzfeldt⁃Jakob disease (CJD) is a degenerative central nervous system (CNS) disease caused by infection of prion protein (PrP), with clinical features including short course, rapid development and 100% mortality.
Lin WANG, Jian-rong LIU
doaj   +5 more sources

Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels [PDF]

open access: goldBMC Public Health, 2005
Background Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results.
Calero Miguel   +5 more
doaj   +2 more sources

Specific early electroencephalogram for the diagnosis of sporadic Creutzfeldt-Jakob disease [PDF]

open access: yesPrion
An early diagnosis is required for intervention in prion disease cases. To elucidate the specificity of early electroencephalography discharges in cases of sporadic Creutzfeldt-Jakob disease, we analysed epileptiform discharges through ...
Taiki Matsubayashi   +5 more
doaj   +2 more sources

Genetic Creutzfeldt-Jakob disease linked to the E200K mutation: a large cohort study. [PDF]

open access: hybridActa Neuropathol
Appleby BS   +8 more
europepmc   +3 more sources

Progressive multifocal diffusion-weighted imaging hyperintensities in sporadic Creutzfeldt–Jakob disease with positive cerebrospinal fluid real-time quaking-induced conversion: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Creutzfeldt–Jakob disease is a rare and invariably fatal neurodegenerative disorder classified among the prion diseases. Primarily affecting the brain, this condition precipitates neuronal cell demise, culminating in swiftly advancing dementia
Puyu Li   +6 more
doaj   +2 more sources

Creutzfeldt–Jakob disease: A case report [PDF]

open access: yesRadiology Case Reports
Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality.
Fahad Rasool Butt, HBSc   +2 more
doaj   +2 more sources

Developing neuropalliative care for sporadic Creutzfeldt-Jakob Disease

open access: yesPrion, 2022
We aimed to identify targets for neuropalliative care interventions in sporadic Creutzfeldt-Jakob disease by examining characteristics of patients and sources of distress and support among former caregivers.
Krista L. Harrison   +6 more
doaj   +1 more source

Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease

open access: yesActa Neuropathologica Communications, 2020
Mitochondrial dysfunction has been implicated in multiple neurodegenerative diseases but remains largely unexplored in Creutzfeldt-Jakob disease. Here, we characterize the mitochondrial respiratory chain at the individual neuron level in the MM1 and VV2 ...
Irene H. Flønes   +7 more
doaj   +1 more source

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