Results 11 to 20 of about 5,030,757 (219)

Efficient transmission and characterization of creutzfeldt-jakob disease strains in bank voles. [PDF]

PLoS Pathogens, 2006
Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model.
Romolo Nonno, Michele A Di Bari, Franco Cardone, Gabriele Vaccari, Paola Fazzi, Giacomo Dell'Omo, Claudia Cartoni, Loredana Ingrosso, Aileen Boyle, Roberta Galeno, Marco Sbriccoli, Hans-Peter Lipp, Moira Bruce, Maurizio Pocchiari, Umberto Agrimi   +14 more
doaj   +3 more sources

Creutzfeldt-Jakob Disease After the Coronavirus Disease-2019 Vaccination

Türk Yoğun Bakim Derneği Dergisi, 2022
Reports of neurological problems are increasing for the clinical presentation of coronavirus disease-2019 (COVID-19). The clinical presentation reported in this study seemed to be a combination of nonspecific complications of the systemic disease ...
Anıl Kuvandık, Ecenur Özcan, Simay Karaduman, Hülya Sungurtekin   +3 more
doaj   +2 more sources

Source of variant Creutzfeldt-Jakob disease outside United Kingdom. [PDF]

, 2007
We studied the occurrence of variant Creutzfeldt-Jakob disease (vCJD) outside the United Kingdom in relation to the incidence of indigenous bovine spongiform encephalopathy (BSE) and to the level of live bovines and bovine products imported from the UK ...
Cousens, Simon N, Cornelia M. van Duijn, Sanchez-Juan, Pascual, Pascual Sanchez-Juan, Will, Robert G, van Duijn, Cornelia M, Robert G. Will, Pascual Sanchez-Juan, Simon N. Cousens   +8 more
core   +1 more source

Beyond PrP res type 1/type 2 dichotomy in Creutzfeldt-Jakob disease [PDF]

, 2008
Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently subclassified according to the methionine/valine polymorphism at codon 129 of the PRNP gene and the proteinase K (PK) digested abnormal prion protein (PrPres)identified on Western blotting ...
Ironside, James W, Uro-Coste, Emmanuelle, Grassi, J., Head, Mark, Jean-Marc Bilheude, Lacroux, Caroline, Cassard Hervé, Armand Perret-Liaudet, Marie Bernadette Delisle, Grassi, Jacques, Head, M.W., Hauw, J.J., Head Mark W., Andréoletti Olivier, Bilheude, Jean-Marc, Peoch, Katell, Delisle, Marie-Bernadette, Streichenberger, Nathalie, Ironside, J.E., Simon Stéphanie, Lacroux Caroline, Simon, S., Haik, S., Peoch' Katell, Hervé Cassard, Jean-Jacques Hauw, Haik Stéphane, Basset-Leobon Christelle, Bilheude, J.M., Andreoletti, O., Jan Langeveld, Bilheude Jean-Marc, Stéphanie Simon, Uro-Coste Emmanuelle, Schelcher, F., Ironside, James, W., Langeveld, Jan, Christelle Basset-Leobon, Jacques Grassi, Olivier Andréoletti, Lugan, Séverine, Andréoletti, Olivier, Emmanuelle Uro-Coste, Lugan, S., Caroline Lacroux, Ironside, James, Hauw, Jean-Jacques, Perret-Liaudet, Armand, Basset-Leobon, Christelle, Basset-Leobon, C., Cassard, Hervé, Stéphane Haik, Head, Mark, W., Hauw Jean-Jacques, Langeveld Jan, James W Ironside, Simon, Stéphanie, Peoch, K., Séverine Lugan, Streichenberger Nathalie, Langeveld, J.P.M., Perret-Liaudet, A., Streichenberger, N., Cassard, H., Delisle, M.B., Uro-Coste, E., Haik, Stéphane, Schelcher, Francois, Grassi Jacques, Peoc’h, Katell, Mark W Head, Delisle, Marie Bernadette, Lacroux, C., Lugan Séverine, Schelcher Francois, Delisle Marie Bernadette, Head, Mark W, Ironside James W., Nathalie Streichenberger, Francois Schelcher, Katell Peoch', Perret-Liaudet Armand, Peoch', Katell, Head, Mark,, Ironside, James,   +84 more
core   +1 more source

Creutzfeldt–Jakob disease [PDF]

Psychogeriatrics, 2011
AbstractCreutzfeldt–Jakob disease (CJD) is a progressive, degenerative, and fatal disease of the central nervous system. It is caused by abnormal accumulation of prion proteins and is characterized mainly by progressive dementia, myoclonus, and cerebellar, pyramidal, and extrapyramidal findings. Psychiatric symptoms may also accompany CJD and are often
Ali Görkem, Gençer, Zerrin, Pelin, Cem İsmail, Küçükali, Ozgür Bilgin, Topçuoğlu, Nuriye, Yilmaz   +4 more
openaire   +2 more sources

Proteomic analysis of the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease [PDF]

, 2007
So far, only the detection of 14-3-3 proteins in cerebrospinal fluid (CSF) has been accepted as diagnostic criterion for Creutzfeldt-Jakob disease (CJD). However, this assay cannot be used for screening because of the high rate of false-positive results,
Steinacker, Petra, Brechlin, Peter, Cepek, Lukas, Klingebiel, Enrico, Bibl, Mirko, Kretzschmar, Hans A., Mollenhauer, Brit, Otto, Markus, Wiltfang, Jens   +8 more
core   +1 more source

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification [PDF]

, 2009
Six subtypes of sporadic Creutzfeldt-Jakob disease with distinctive clinico-pathological features have been identified largely based on two types of the abnormal prion protein, PrPSc, and the methionine (M)/valine (V) polymorphic codon 129 of the prion ...
Maurizio Pocchiari, Roncaroli F, Cras, Patrick, Patrich Cras, Anna Ladogana, Giese, Armin, Cras, Patrich, Pocchiari M, Ladogana, Anna, Federico Roncaroli, Ladogana A, Bernardino Ghetti, Jan P. M. Langeveld, Strammiello, R., Zerr, I., Ghetti, B., Ghetti B, Roncaroli, Federico, Pocchiari, Maurizio, Langeveld, Jan P.M., Inga Zerr, Cras, P., Notari, Silvio, Cras P, Giese, A., Roncaroli, F., Parchi, Piero, Notari, S., Kretzschmar H, Langeveld JP, Rosaria Strammiello, Ghetti, Bernardino, Zerr, Inga, Kretzschmar, Hans A., Armin Giese, Parchi, P., Capellari, S., Hans Kretzschmar, Notari S, Pocchiari, M., Kretzschmar, Hans, Ladogana, A., Giese A, Langeveld, J.P.M., Capellari, Sabina, Strammiello, Rosaria, Piero Parchi, Silvio Notari, Zerr I, Langeveld, Jan P. M., Kretzschmar, H., Sabina Capellari   +51 more
core   +1 more source

Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review

Health Technology Assessment, 2020
Background: Creutzfeldt–Jakob disease is a fatal neurological disease caused by abnormal infectious proteins called prions. Prions that are present on surgical instruments cannot be completely deactivated; therefore, patients who are subsequently ...
Matt Stevenson, Lesley Uttley, Jeremy E Oakley, Christopher Carroll, Stephen E Chick, Ruth Wong   +5 more
doaj   +1 more source

Sporadic Creutzfeldt-Jakob disease with cerebellar ataxia at onset in the UK [PDF]

, 2006
To determine the frequency, in the UK, of sporadic Creutzfeldt-Jakob Disease (sCJD) with a cerebellar ataxic onset, and to describe the clinical features of the ...
Will, R G, Heath, C A, Cooper, S A, Knight, R S G, Murray, K L   +4 more
core   +1 more source

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Niedmann, P., Poser, S., Otto, M., Kretzschmar, Hans A., Otto, Markus, Poser, Sigrid, Schmidt, H., Schroter, A., Kretzschmar, H. A.   +9 more
core   +1 more source